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Flashcards in Pituitary/Adrenal Glands Deck (19):
1

PNMT converts ______ to _______;
found only in ________

norepinephrine to epinephrine; found only in the adrenal medulla

2

Pheochromocytoma rule of ten's (x5)

10% are: malignant, bilateral, in children, part of MEN, extra-adrenal (organ of Zuckerkandi at Ao bifurcation= most common)

3

Pheochromocytoma:
Preop meds: ________ then _______ if ________

alpha block first, then beta block if tachycardic

4

Pheochromocytoma tests:
screen with ______, _________;
___ can localize

urine metanephrines, VMA;
MIGB can localize

5

Nelson syndrome: _____%
____, ___, ___

post adrenalectomy (10%);
incr ACTH, pigmentation, vision changes from incr pituitary response

6

Waterhouse Friedrickson

adrenal hemorrhage a/w meningococcal sepsis

7

Conn's Syndrome= ________
Causes: 80% _____, 20% _____;
labs, vitals? _________

hyperaldosteronism= 80% adenoma, 20% bilateral hyperplasia (see with postural stimulation test). HTN, low K, high Na

8

Addison's disease= __________;
labs: ___________;
crisis similar to _________;
________ are diagnostic and therapeutic

low aldosterone and glucocorticoids;
low Na, high K, hypoglycemia;
crisis presents similar to sepsis with hypoTN, fever;
STERIODS are diagnostic and therapeutic

9

Most common congenital adrenal hyperplasia

21-hydroxylase deficiency

10

Cushing' sundrome= excess _________, most commonly ______

excess steroids; most commonly iatrogenic

11

Pituitary (Cushing's Disease): ___% of non-iatrogenic;
lab: __________
High dose steroid test effect? _____

70% of non-iatrogenic; high ACTH, suppresses with high dose steroid test

12

Adrenal Cushing's Syndrome: ___% of non-iatrogenic;
lab: ______
high dose steroid test effect? ____

15% of non-iatrogenic; low ACTH, independent steroid production, dose not suppress with test

13

Ectopic cushing's syndrome:
_____ produced elsewhere,
usually seen in ______
high dose steroid test effect? ____

ACTH produced elsewhere, usually small cell CA, does not suppress with test

14

Posterior pituitary: aka (neuro- or adeno hypophysis)?
Produces: _________________

=neurohypophysis;
produces ADH, Oxytocin

15

Anterior pituitary: aka (neuro-or adeno-hypophysis)?
Produces: _____________

=adenohypophysis;
produces GH, ACTH, TSh, LH, FSH, prolactin

16

Bitemporal hemianopsia is classic vision change with
_______________________________

pituitary mass effect

17

Chromophobe pituitary adenoma

non-functional, see decr GH, FSH, LH, TSH, ACTH

18

#1 pituitary adenoma?
Symptoms?
Rx?

Prolactinoma;
galactorrhea, irregular menses;
bromocriptineor trans-sphenoidal resection

19

Sheehan Syndrome

postpartum lack of lactation, persistent amenorrhea