Breast cancer Flashcards
(9 cards)
where do most breast cancers arise from
duct tissue
second most common: lobular tissue
what is Paget’s disease
an eczemoid change of the nipple (unilateral) associated with an underlying malignancy
what age should women be offered screening
47-73
give some risk factors for the development of breast cancer
BRCA1/2 gene early menarche, late menopause not breastfeeding p53 gene mutation obesity COCP/HRT nulliparity/first child >30 ionising radiation previous surgery for benign disease
if tumours are ER+ve what can you give as an adjunct
hormonal therapy
tamoxifen for pre/peri menopausal women
aromatase inhibitors for post-menopausal women
what investigations should you do in suspected breast cancer
mammogram USS MRI FNAC biopsy
CXR
bloods
USS liver
sentinel lymph node biopsy
what should all HER2+ve who receive chemotherapy receive for a further 6-12 months
Herceptin
describe what follow-up you should do from years 1-5
year 1 = clinical examination + mammogram
year 2 -4 = mammogram only
year 5 = clinical examination and mammogram
how often should women be screened for breast cancer
every 3 years
