Goserelin Flashcards
(5 cards)
1
Q
how is goserelin administered
A
as an injection every 4 weeks
2
Q
what is goserelin used for
A
prostate cancer
ER+ve breast cancer
3
Q
what are some side effects of goserelin
A
tumour flare
skin rash
hot flushes
sore joints
change in BP/BM
tiredness
ED/loss of libido
4
Q
what are three long term effects of goserelin
A
osteoporosis
weight gain
heart problems
5
Q
how does goserelin work
A
downregulation of GnRH receptors, therefore reducing the release of gonadotrophin
inhibition of androgen and oestrogen production
