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Flashcards in breast pathology Deck (30)
1

what race has highest risk for breast cancer

Af Am

2

most likely located of malignant breast tumors

upper outer quadrant

3

what type of receptor has the worst prognosis

triple negative

4

single most important prognostic factor

axillary LN involvement

5

of types of invasive carcinoma, which is most common?

ductal carcinoma

6

2nd most common type of invasive carcinoma?

lobular carcinoma

7

stage 2 breast cancer has a 5 year survival of ____

75%

8

what is the single most important prognositc factor

axillary LN involvement

9

early malignancy that fills ductal lumen without basement membrane penetration

DCIS

10

DCIS presents with what on mammography

microcalcifications

11

subtype of DCIS with ductal caseous necrosis surrounded by cancer cells

comedocarcinoma

12

ezcematous patches on nipples that results from underlying DCIS

paget disease

13

large cells with clear halo

paget cells

14

what has the worst prognosis

invasive ductal carcinoma

15

firm, fibrous, rock hard mass with sharp margins

invasive ductal carcinoma

16

small duct like or glandular cells with collagenous stroma

invasive ductal carcinoma

17

bilateral with multiple lesions in the same location; orderly row of cells

invasive lobular carcinoma

18

what type of invasive carcinoma: fleshy, cellular, lymphocytic infiltrate, good prognosis

medullary carcinoma

19

what type of invasive carcinoma: dermal lymphatic invasion, peau d'orange, neoplastic cells block lymph drainage

inflammatory carcinoma

20

most common tumor in patients under 35

fibroadenoma

21

is fibroadenoma a precursor to cancer?

no

22

small firm mobile mass with sharp edges

fibroadenoma

23

small mass that grows in lactiferous ducts & beneath areola w/ serous/bloody nipple discharge

intraductal papilloma

24

is intraductal papilloma a precursor to cancer?

yes, incr risk for breast cancer

25

fast growing mas that forms from periductal stromal cells; leaf like projections, postmenopausal

phyllodes tumor

26

most common cause of breast lumps age 25-menopause

proliferative breast disease

27

incr acini and intralobular fibrosis; assc'd with calcification

sclerosing adenosis

28

patients >30 yo, incr in #epithelial cell layers in terminal duct lobules

epithelial hyperplasia

29

what pathogen is most commonly responsible for acute mastitis?

S aureus

30

post trauma, mass in breast with abnormal calcification

fat necrosis with giant cells