Flashcards in puberty Deck (40)
1
secretion of sex steroid hormones after regeneration fo the zona reticularis in the adrenal cortex is?
adrenarche
2
when does adrenarche occur?
age 6-8
3
when does gonadarche begin?
age 8
4
pulsatile gnRH is incr without phenotypic changes is what stage?
gonadarche
5
when breast bud development begins
thelarche
6
thelarche begins when
11
7
breast buds are generated in response to _____
estrogen
8
onset of pubic hair growth around age 12
pubarche
9
pubarche normally precedes menarche by____
2 years
10
when does menarche usu occur?
age 12-13
11
how long does it take for regular ovulatory menstrual cycles to occur?
2 yrs
12
FSH is responsible for synthesis of____, whereas LH is responsible for synthesis of ____
estrogen; progesterones & androgens
13
vagine is ____cm at birth, grows ___cm during early childhood, incr to ____late childhood
4; 1; 7-8.5
14
after menarche what happens to uterine corpus: cervix ratio?
3:1
15
at what age does gnRH become enhanced during sleep
8
16
growth peak is ___years after breast budding and ___year before menarache
2; 1
17
sexual maturation typically takes____yrs
4.5
18
precocious puberty is defined as breast development before___, pubic hair before___, menstruation before____
age 7; age 8; age 10
19
multiple bone fracures, cafe au lait spots, gnrh independent precocious puberty
mccune albright syndrome
20
tx of choice for GnRH dependent precocious puberty
GnRH agonists
21
best assessment for skeletal maturation?
bone age
22
delayed puberty is no secondary sex characteristics by____; no menarche by____, no menses initiation ____after thelarche
13 yo; 15-16 yo; 5 years
23
most common cause of delayed puberty with incr FSH is
Turners syndrome
24
tx of turners
1. GH initiated early
2. estrogen when puberty would normally start
3. delay progestins until Tanner stage IV
25
most common tumor assc'd with delayed puberty
craniopharyngioma
26
hypoplastic olfactory tracts, no secretion of gnRH from arcuate nucleus, no breast development
kallmann syndrome
27
how to tx kallman syndrome
exogenous hormones or admin of pulsatile GnRH
28
most common cause of primary ameorrhea in women with normal breast development
mullerian agenesis
29
congenital absence of vagina, uterus, fallopian tubes; normal ovarian fxn
mullerian agenesis
30
present with pelvic pain and bulging bluish vaginal introitus
imperforate hymen
31
tanner stage: elevation of papilla only
stage B1
32
tanner stage: elevation of breast, papilla as small mound, enlargement of areolar diameter
stage B2
33
tanner stage: enlargement of breast & areola with no separation of contours
stage B3
34
tanner stage: further enlargement with projection of areola and papilla to form a secondary mound above the level of the breast
stage B4
35
tanner stage: projection of papilla only, resulting from recession of the areola to the general contour of the breast
stage B5
36
tanner stage: no pubic hear
stage PH1
37
tanner stage: sparse growth of long, slightly pigmented, downy hair, straight or only slightly curled, appearing chiefly along the labia
stage PH2
38
tanner stage: hair darker, coarser, and curlier; spreads to extend sparsely over the junction of the pubes
stage PH3
39
tanner stage: hair adult in type; spreads over the mons but not to the medial surface of the thighs
stage PH4
40