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Flashcards in puberty Deck (40)
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1

secretion of sex steroid hormones after regeneration fo the zona reticularis in the adrenal cortex is?

adrenarche

2

when does adrenarche occur?

age 6-8

3

when does gonadarche begin?

age 8

4

pulsatile gnRH is incr without phenotypic changes is what stage?

gonadarche

5

when breast bud development begins

thelarche

6

thelarche begins when

11

7

breast buds are generated in response to _____

estrogen

8

onset of pubic hair growth around age 12

pubarche

9

pubarche normally precedes menarche by____

2 years

10

when does menarche usu occur?

age 12-13

11

how long does it take for regular ovulatory menstrual cycles to occur?

2 yrs

12

FSH is responsible for synthesis of____, whereas LH is responsible for synthesis of ____

estrogen; progesterones & androgens

13

vagine is ____cm at birth, grows ___cm during early childhood, incr to ____late childhood

4; 1; 7-8.5

14

after menarche what happens to uterine corpus: cervix ratio?

3:1

15

at what age does gnRH become enhanced during sleep

8

16

growth peak is ___years after breast budding and ___year before menarache

2; 1

17

sexual maturation typically takes____yrs

4.5

18

precocious puberty is defined as breast development before___, pubic hair before___, menstruation before____

age 7; age 8; age 10

19

multiple bone fracures, cafe au lait spots, gnrh independent precocious puberty

mccune albright syndrome

20

tx of choice for GnRH dependent precocious puberty

GnRH agonists

21

best assessment for skeletal maturation?

bone age

22

delayed puberty is no secondary sex characteristics by____; no menarche by____, no menses initiation ____after thelarche

13 yo; 15-16 yo; 5 years

23

most common cause of delayed puberty with incr FSH is

Turners syndrome

24

tx of turners

1. GH initiated early
2. estrogen when puberty would normally start
3. delay progestins until Tanner stage IV

25

most common tumor assc'd with delayed puberty

craniopharyngioma

26

hypoplastic olfactory tracts, no secretion of gnRH from arcuate nucleus, no breast development

kallmann syndrome

27

how to tx kallman syndrome

exogenous hormones or admin of pulsatile GnRH

28

most common cause of primary ameorrhea in women with normal breast development

mullerian agenesis

29

congenital absence of vagina, uterus, fallopian tubes; normal ovarian fxn

mullerian agenesis

30

present with pelvic pain and bulging bluish vaginal introitus

imperforate hymen