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Flashcards in endocrinology Deck (35)
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1

avg duration of female monthly cycle

20-45 days

2

endometrial proliferation takes place during follicular or luteal phase?

follicular

3

follicular phase is followed by____, luteal phase is followed by_____

ovulation; menses

4

when does the corpus luteum form?

luteal phase

5

GnRH is released in what sort of manner?

pulsatile

6

there is a pulsatile release of LH every____

90 min

7

FSH rises ________

early in follicular phase

8

peak concentrations of steroids occur when?

right before ovulation

9

where are inhibin A & B synthesized?

granulosa cells of ovary

10

inhibin A is secreted from____, Inhibin B is secreted from____

corpus luteum; granulosa cells

11

inhibin B regulates ant pit to decr secretion of_____

FSH

12

follicular phase is associated with_____synthesis

estrogen

13

during the follicular phase, proliferation of the uterin endometrium is regulated by?

estrogen

14

what induces ovulation?

the surge of FSH & LH at day 14

15

what hormone is absoultely req'd for ovulation?

LH

16

what is a temporary endocrine gland?

corpus luteum

17

when does the corpus luteum reach a mature state?

7-8 days following ovulation

18

what is the regulatory hormone of steroid synthesis in luteal phase?

LH

19

what is the regulatory hormone of steroid synthesis in follicular phase?

LH & FSH

20

differentiation of the uterine endometrium is regulated by?

progesterone

21

what exerts negative feedback at the end of the luteal pahse?

1. progesterone
2. inhibin A

22

break down of the zona pellucida

hatching

23

trophoblastic cells of the blastocyst makes contact with endometrium

apposition

24

trophoblasts differentiates into (2)

1. cytotrophoblasts
2. syncytiotrophoblasts

25

what cell types sends out protrusions and invades the endometrium

syncytiotrophoblasts

26

what stimualtes ovarian steroidogenesis for 1st 8 weeks after implantation?

HcG

27

when does hcg production peak?

10 weeks

28

think of what hormone for growth, development, metabolism of fetus?

hpl

29

what happens to hpl over the course of pregnancy?

increases

30

_______produce both Hcg and hpl

syncytiotrophoblasts

31

hpl starts getting secreted at ______

6 weeks

32

CRH is produced by _____and____

syncytiotrophoblasts and trophoblasts

33

what hormone induces the onset of labor and PG production?

CRH

34

what hormone inhibs PG production and suppresses uterine contraction?

progesteron and 17-OH progesterone

35

what provides substrates for estrogen synthesis?

DHEA