endocrinology Flashcards

(35 cards)

1
Q

avg duration of female monthly cycle

A

20-45 days

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2
Q

endometrial proliferation takes place during follicular or luteal phase?

A

follicular

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3
Q

follicular phase is followed by____, luteal phase is followed by_____

A

ovulation; menses

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4
Q

when does the corpus luteum form?

A

luteal phase

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5
Q

GnRH is released in what sort of manner?

A

pulsatile

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6
Q

there is a pulsatile release of LH every____

A

90 min

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7
Q

FSH rises ________

A

early in follicular phase

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8
Q

peak concentrations of steroids occur when?

A

right before ovulation

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9
Q

where are inhibin A & B synthesized?

A

granulosa cells of ovary

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10
Q

inhibin A is secreted from____, Inhibin B is secreted from____

A

corpus luteum; granulosa cells

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11
Q

inhibin B regulates ant pit to decr secretion of_____

A

FSH

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12
Q

follicular phase is associated with_____synthesis

A

estrogen

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13
Q

during the follicular phase, proliferation of the uterin endometrium is regulated by?

A

estrogen

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14
Q

what induces ovulation?

A

the surge of FSH & LH at day 14

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15
Q

what hormone is absoultely req’d for ovulation?

A

LH

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16
Q

what is a temporary endocrine gland?

A

corpus luteum

17
Q

when does the corpus luteum reach a mature state?

A

7-8 days following ovulation

18
Q

what is the regulatory hormone of steroid synthesis in luteal phase?

19
Q

what is the regulatory hormone of steroid synthesis in follicular phase?

20
Q

differentiation of the uterine endometrium is regulated by?

21
Q

what exerts negative feedback at the end of the luteal pahse?

A
  1. progesterone

2. inhibin A

22
Q

break down of the zona pellucida

23
Q

trophoblastic cells of the blastocyst makes contact with endometrium

24
Q

trophoblasts differentiates into (2)

A
  1. cytotrophoblasts

2. syncytiotrophoblasts

25
what cell types sends out protrusions and invades the endometrium
syncytiotrophoblasts
26
what stimualtes ovarian steroidogenesis for 1st 8 weeks after implantation?
HcG
27
when does hcg production peak?
10 weeks
28
think of what hormone for growth, development, metabolism of fetus?
hpl
29
what happens to hpl over the course of pregnancy?
increases
30
_______produce both Hcg and hpl
syncytiotrophoblasts
31
hpl starts getting secreted at ______
6 weeks
32
CRH is produced by _____and____
syncytiotrophoblasts and trophoblasts
33
what hormone induces the onset of labor and PG production?
CRH
34
what hormone inhibs PG production and suppresses uterine contraction?
progesteron and 17-OH progesterone
35
what provides substrates for estrogen synthesis?
DHEA