Flashcards in endocrinology Deck (35)
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1
avg duration of female monthly cycle
20-45 days
2
endometrial proliferation takes place during follicular or luteal phase?
follicular
3
follicular phase is followed by____, luteal phase is followed by_____
ovulation; menses
4
when does the corpus luteum form?
luteal phase
5
GnRH is released in what sort of manner?
pulsatile
6
there is a pulsatile release of LH every____
90 min
7
FSH rises ________
early in follicular phase
8
peak concentrations of steroids occur when?
right before ovulation
9
where are inhibin A & B synthesized?
granulosa cells of ovary
10
inhibin A is secreted from____, Inhibin B is secreted from____
corpus luteum; granulosa cells
11
inhibin B regulates ant pit to decr secretion of_____
FSH
12
follicular phase is associated with_____synthesis
estrogen
13
during the follicular phase, proliferation of the uterin endometrium is regulated by?
estrogen
14
what induces ovulation?
the surge of FSH & LH at day 14
15
what hormone is absoultely req'd for ovulation?
LH
16
what is a temporary endocrine gland?
corpus luteum
17
when does the corpus luteum reach a mature state?
7-8 days following ovulation
18
what is the regulatory hormone of steroid synthesis in luteal phase?
LH
19
what is the regulatory hormone of steroid synthesis in follicular phase?
LH & FSH
20
differentiation of the uterine endometrium is regulated by?
progesterone
21
what exerts negative feedback at the end of the luteal pahse?
1. progesterone
2. inhibin A
22
break down of the zona pellucida
hatching
23
trophoblastic cells of the blastocyst makes contact with endometrium
apposition
24
trophoblasts differentiates into (2)
1. cytotrophoblasts
2. syncytiotrophoblasts
25
what cell types sends out protrusions and invades the endometrium
syncytiotrophoblasts
26
what stimualtes ovarian steroidogenesis for 1st 8 weeks after implantation?
HcG
27
when does hcg production peak?
10 weeks
28
think of what hormone for growth, development, metabolism of fetus?
hpl
29
what happens to hpl over the course of pregnancy?
increases
30
_______produce both Hcg and hpl
syncytiotrophoblasts
31
hpl starts getting secreted at ______
6 weeks
32
CRH is produced by _____and____
syncytiotrophoblasts and trophoblasts
33
what hormone induces the onset of labor and PG production?
CRH
34
what hormone inhibs PG production and suppresses uterine contraction?
progesteron and 17-OH progesterone
35
