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Flashcards in Brucella Deck (22)
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1
Q

What are the 4 important Brucella species?

A

B. melitensis
B. abortus
B. suis
B. canis

2
Q

What is the principle cause of human brucellosis?

A

B. melitensis

3
Q

What is the pathogenesis of B. abortus?

A
No symptoms 
Spreads intracellular 
1-6 weeks incubation period 
Regional lymphonodus
Target organs
4
Q

What is the pathogenesis of B. abortus in the uterus?

A

Placentoma and multiplication -> excretion and spread to bovines and humans

5
Q

What is the pathogenesis of B. abortus in the fetus?

A

Fetus and multiplication
Abortion
Premature birth
Normal partus but calf is carrier

6
Q

What is the pathogenesis of B. abortus in the udder?

A

Subclinical mastitis

Excretion and spread

7
Q

How does B. abortus affect immunity?

A

When cellular immunity is not capable of killing all intracellular bacteria

8
Q

How would B. abortus be Dx?

A
SAW or SAT
Rose bengal test simple 
CFT
ELISA
IFN-gamma
Skin test
Bacteriology
9
Q

What are the 3 types of test done for Brucellosis?

A

Brucellergen (skin) test
EU regulation
IFN-gamma test

10
Q

What is tested for first to make sure you are dealing with Brucella?

A

IFN-gamma

11
Q

T/F: Brucella suis is still present in wildlife

A

True

12
Q

What are the 2 biovars pathogenic in pigs?

A

Biovar 1: reservoir in hares
Biovar 2: reservoir in hares
Biovar 3: reservoir in pigs

13
Q

What are the CS of B. suis?

A
Abortion
Orchitis 
Infertility 
Athritis 
Tendovaginitis 
Bursitis 
Osteomyelitis
14
Q

What is the pathogenesis of B. suis?

A

Skin/mucosa -> regional lymph nodes -> bacteremia -> localization and abscess formation

15
Q

How is Brucellosis Dx in wild boar?

A

Yersinia enterocolitica O9

Serological tests

16
Q

B. melitensis mainly affects what animals?

A

Mainly sheep and goats

17
Q

Where is B. melitensis mainly located?

A

Subtropical and mediterranean countries

18
Q

Between B. abortus and B. melitensis, which one is worse off with zoonosis?

A

B. melitensis

19
Q

T/F: B. ovis is zoonotic

A

False

20
Q

Why is the prevalence of B. canis increasing?

A

Breeding facilities

21
Q

What are the symptoms of B. canis?

A
Long bacteremia, no fever
Lymphadenitis 
Late abortion 
Vaginal discharge 
Epididymitis 
Scrotum dermatitis 
Atrophia testiculaire 
Prostatis 
STD
22
Q

T/F: D. canis can have false positive and false negative serological results

A

True