Pseudomonas Flashcards

(52 cards)

1
Q

T/F: Pseudomonas can be found mainly in waters

A

True

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2
Q

How is P. aeruginosa able to cause secondary infection?

A

Facultative pathogenic

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3
Q

What are some general features of P. aeruginosa ?

A
Facultative symbiotic 
Easy grower
Large colonies 
Typical candy sweet odor 
Blue-green pigmentation 
Oxidase positive 
Lactose Negative
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4
Q

What are the environmental origins of P. aeruginosa infections?

A

High natural resistance

Can adapt to humid hospital environments

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5
Q

What are the virulence factors of P. aeruginosa?

A
Adhesion
LPS
Exotoxins
Biofilm
Capsule 
Iron acquisition
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6
Q

What kind of animals do P. aeruginosa affect?

A

Cold blood animals

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7
Q

Where are the predisposing factors of P. aeruginosa

A

High infection pressure
Humidity
Reduced immunity

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8
Q

What are the CS of P. aeruginosa in cats and dogs?

A
Pyoderma 
Cystitis 
Otitis externa 
Purulent processes
Corneal ulcers
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9
Q

What are the CS of P. aeruginosa in hamster, guinea pig, chinchilla, mink?

A

Pneumonia
Septicaemiae
High mortality

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10
Q

What is the origin of P. aeruginosa in hamster, guinea pig, chinchilla, mink?

A

Mainly drinking water

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11
Q

What are the CS of P. aeruginosa in rabbit?

A

Skin infection = dermatitis

Pneumonia

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12
Q

What are the CS of P. aeruginosa in Horses?

A
Metritis-vaginitis 
Keratitis conjunctivitis (secondary infection)
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13
Q

What are the CS of P. aeruginosa in bovine, sheep, and goat?

A

Mastitis
Fleece rot
Acute with high mortality
Persistence in udder, even after Tx

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14
Q

What are the CS of P. aeruginosa in reptiles?

A

Necrotic stomatitis
Pneumonia
Septicaemiae
Secondary to poor housing

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15
Q

What are the CS of P. aeruginosa in parrots and parakeets (psittaciformes)?

A
Secondary infection mainly from drinking water 
Conjunctivitis 
Rhinitis 
Pneumonia 
Enteritis
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16
Q

What are the CS of P. aeruginosa in Galliformes?

A

In oviduct of turkeys
Contamination of eggs
Complication of viral infection

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17
Q

What is the number one way to Tx Pseudomonas aeruginosa?

A

Take away cause of infection

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18
Q

What are some characteristics of Burkholderia?

A

Gram negative
Aerobic
Rods
Catalase positive

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19
Q

What are two species of Burkholderia?

A

B. mallei

B. pseudomallei

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20
Q

What are the CS of B. mallei?

A
Glanders via BSL3 agent 
Nodules and ulcers, pyogranulomatous 
Orchitis
Skin Respiratory tract 
Great variability in severity
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21
Q

B. mallei is a pathogen is primarily in what species?

22
Q

T/F: B. mallei is a reportable disease

23
Q

How is B. mallei transmitted?

A

Ingestion of feed and water
Inhalation
Wounds

24
Q

What are the acute symptoms of a B. mallei glanders infection?

A

Fever
Nasal discharge
Lymphadenitis
Frequently fatal

25
What are the chronic symptoms a B. mallei glanders infection?
Should not see Fever and respiratory problems Skin abscesses
26
T/F: B. mallei is zoonotic
True
27
What is the pathogenesis of B. mallei?
Entry -> Spread via Lymph/blood -> Nodular lesions in lymph nodes, lung, liver, spleen
28
What is the official test to Dx B. mallei?
Horses CFT, but can create sometimes false positives
29
T/F: There are vaccinations available for B. mallei
False, no vaccine available
30
What kind of infection does B. pseudomallei cause?
Melioidosis (pyogranulomatous infection)
31
How is B. pseudomallei, Melioidosis transmitted?
Ingestion, wound infection, airborne, arthropod bites
32
What are the virulence factors of B. pseudomallei, Melioidosis?
Adhesins-flagella Capsule T3SS and T4SS
33
What are the CS of B. pseudomallei, Melioidosis infection in dogs?
Febrile diseases with localizing suppurative foci | Important in military dogs
34
What are the CS of B. pseudomallei, Melioidosis infection in equine?
Mimics glanders = pseudoglanders
35
What are the CS of B. pseudomallei, Melioidosis infection in Cattle?
Acute to chronic | Lungs, joints and uterus
36
What are the CS of B. pseudomallei, Melioidosis infection in Sheep?
Arthritis and lymphadenitis
37
What are the CS of B. pseudomallei, Melioidosis infection in goat?
``` Loss of condition Respiratory and CNS disturbances Arthritis Mastitis Abortion and diarrhea ```
38
T/F: Francisella tularensis is not a reportable disease
False, it is reportable and highly contagious (Zoonotic)
39
What are some important characteristics of F. tularensis?
Gram negative Obligate aerobic Facultative intracellular Very fastidious growth
40
What are the reservoirs for F. tularensis?
Infected lagomorphs Rodents Amoeba
41
How is F. tularensis transmitted?
Ticks, mosquito's, flies Contaminated waters Ingestion of infected pray
42
What are the subspecies of F. tularensis?
Mediasiatica Holartica Tularensis (Novicida)
43
What is the clinical presentation of F. tularensis?
Rare, CS rarely seen | Mainly liver, spleen, lungs affected
44
How does Taylorella equigenitalis affect male and female horses?
Male: No symptoms and no immunity Female: Contagious Equine Metritis (CEM) Immunity
45
What are the CS of CEM in females with T. equigenitalis?
``` Acute suppurative Self limiting Temporary sterility Highly contagious Become asymptomatic carriers Immunity ```
46
T/F: T. equigenitalis has environmental resistance
True, but it is poor; max 2 days in fridge
47
What is the epidemiology T. equigenitalis?
Exclusively in equine genital tract Control by regular sampling of breeding stallions STD
48
What is the pathogenesis of T. equigenitalis in mares?
Spontaneous healing Temporary infertility Few abortions May cause infection of newborns
49
Where do you sample in stallions for T. equigenitalis?
Preputium Urethra Fossa glandis and Sinus urethralis
50
Where do you sample in mares for T. equigenitalis?
Fossa clitoridis | Sinus clitoridis
51
How would T. equigenitalis be prevented?
Elimination of positive animals from breeding | Vaccination
52
What is the Tx plan for T. equigenitalis?
Treat uterine infection with intrauterine and systemic application of antibiotics