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Flashcards in buncha meds Deck (67):
1

nimodipine (Nimotop)
MOA only

MOA: CCB - counters vasospasms by preventing Ca from entering smooth muscle cells + causing contraction (CVA)

2

ticlopidine (Ticlid)

MOA: anti-platelet

3

ticlopidine considerations

aka Ticlid
AE: assoc w agranulocytosis, thrombotic thrombocytopenia purpura, GI intolerance

4

pyridostigmine (Prostigmin)

MOA: anticholinesterase - block hydrolysis of ACh
indication: symptomatic improvement in myasthenia gravis

5

edrophonium (Tensilon)

MOA: ultra short-acting AChE inhbitor
indication: distinguish between myasthenia crisis & cholinergic crisis

6

carbidopa-levodopa (Sinemet)

MOA: increase available dopamine
indication: Parkinson's Disease mgmt

7

amantadine (Symmetryl)

MOA: increase available dopamine
indication: Parkinson's Disease mgmt

8

pramipexole (Mirapex)

MOA: increase available dopamine
indication: Parkinson's Disease mgmt

9

ropinirole (Requip)

MOA: increase available dopamine
indication: Parkinson's Disease mgmt

10

benztropine (Cogentin)

MOA: anticholinergic (alleviate tremor, rigidity)
indication: Parkinson's Disease mgmt

11

trihexyphenyldyl (Artane)

MOA: anticholinergic (alleviate tremor, rigidity)
indication: Parkinson's Disease mgmt

12

donepezil (Aricept) = memory improvement

MOA: acetylcholinesterase inhibitor
indication: Alzheimer's (specifically, memory improvement)

13

rivastigmine (Exelon)

MOA: acetylcholinesterase inhibitor
indication: Alzheimer's

14

albuterol (Proventil)

MOA: short-acting beta-2 adrenergic agonist (SABA), bronchodilates
indication: asthma rescue, sx relief/breakthrough, or pre-exercise; or inpt mgmt

15

budesonide (Pulmicort)

MOA: inhaled corticosteroid
indication: daily maintenance tx for asthma + increase if sx persist

16

triamcinolone (Azmacort)

MOA: inhaled corticosteroid
indication: daily maintenance tx for asthma + increase if sx persist

17

salmeterol (Serevent)

MOA: long-acting beta-2 adrenergic agonist (LABA)
indication: persistent asthma symptoms

18

ipratropium bromide (Atrovent)

MOA: inhaled anticholinergic
indication: asthma adjunct for secretion mgmt, also inpt mgmt

19

montelukast (Singulair)

MOA: antileukotriene
indication: chronic asthma - stabilization

20

alupent

MOA: inhalation sympathomimetic
indication: inpt mgmt of asthma

21

methylprednisolone 60 - 125 mg IV

MOA: corticosteroid
indication: inpt mgmt of asthma for pts who do not respond to sympathomimetics

22

aqueous epinephrine 1:1000 0.1 - 0.5 mL SQ

MOA: parenteral sympathomimetic
indication: asthma tx for inpt unable to cooperate

23

TB drug doses

Rifampin 600 mg
Isoniazid 300 mg
Pyrazinamide 1.5 - 2.0 g
Ethambutol 15 mg/kg

24

hydrocodone-APAP: generic for which 2 brands

Vicodin, Lortab

25

amitriptyline (Elavil) class x2

antidepressant & neuropathic pain

26

sumatriptan (Imitrex)

MOA: triptan, 5-HT agonist
uses: acute migraine

27

acetazolamide (Diamox)

MOA: carbonic anhydrase inhibitor, inhibits renal tubule H+ excretion (increases Na, K, bicarb, H2O excretion) producing alkaline diuresis
uses: metabolic alkalosis

28

dantrolene sodium (Dantrium) is a treatment for

Serotonin Syndrome

29

diazepam

Valium

30

lorazepam

Ativan

31

midazolam

Versed

32

butorphanol (Stadol) use

opioid toxicity reversal

33

flumazenil (Romazicon) use

benzo toxicity reversal

34

calcineurin inhibitors x2

tacrolimus (Prograft)
cyclosporine

can use for transplant rejection prophylaxis

35

antimetabolites x 2

azathioprine (Imuran)
mycophenolate mofetil (Cellcept)

can use for transplant rejection prophylaxis

36

glipizide (Glucotrol)

MOA: sulfonylurea - stimulate pancreas to release more insulin
indication: diabetic oral agent

37

glyburide (Diabeta)

MOA: sulfonylurea - stimulate pancreas to release more insulin
indication: diabetic oral agent

38

glimepiride (Amaryl)

MOA: sulfonylurea - stimulate pancreas to release more insulin
indication: diabetic oral agent

39

acarbose (Precose)

MOA: alpha-glucosidase inhibitor - bind to disaccharidases more readily than sucrose, therefore less glucose absorbed by gut
indication: oral antidiabetic

40

miglitol (Glyset)

MOA: alpha-glucosidase inhibitor - bind to disaccharidases more readily than sucrose, therefore less glucose absorbed by gut
indication: oral antidiabetic

41

rosiglitazone maleate (Avandia)

MOA: "glitazone" - decrease gluconeogenesis
indication: oral antidiabetic

42

pioglitazone hydrochloride (Actos)

MOA: "glitazone" - decrease gluconeogenesis
indication: oral antidiabetic

43

repaglinide (Prandin)

MOA: non-sulfonylurea insulin release stimulator - rapidly abs from intestine & mimics effect of rapid-acting insulin
indication: indication: oral antidiabetic

44

nateglinide (Starlix)

MOA: non-sulfonylurea insulin release stimulator - rapidly abs from intestine & mimics effect of rapid-acting insulin
indication: indication: oral antidiabetic

45

ACE inhibitor MOA*

block RAAS system @ angiotensin II

46

thiazide diuretics MOA*

⊣ reabs Na + Cl in distal tubule → ↑ urinary excretion Na + H2O

Direct arteriolar vasodilation.

47

loop diuretics MOA*

K EXCRETED

⊣ reabs Na + Cl in proximal + distal tubules + loop of Henle (Na-K-Cl co-transporter = K reabs)

interferes with Cl-binding cotransport system, → ↑ excretion Na, H2O, Ca, Mg, Cl

48

spironolactone MOA*

K SPARED

competes with aldosterone @ distal tubule receptors

↑ Na Cl + H2O excretion while conserving K + H

49

diltiazem class

CCB

50

amlodipine class

CCB

51

prazosin (Minipress)

MOA: alpha-1 antagonist - causes vasodilation
indication: BPH, htn adjunct

52

terazosin (Hytrin)

MOA: alpha-1 antagonist - causes vasodilation
indication: BPH, htn adjunct

53

doxazosin (Cardura)

MOA: alpha-1 antagonist - causes vasodilation
indication: BPH, htn adjunct

54

clonidine (Catapres)

MOA: central alpha-2 agonist - prevents vasoconstriction, causes vasodilation, negative chronotrope
indication: hypertension adjunct

55

methyldopa (Aldomet)

MOA: central alpha-2 agonist - prevents vasoconstriction, causes vasodilation, negative chronotrope
indication: hypertension adjunct

56

minodixil (Loniten)

MOA: arterial vasodilator - directly relaxes vascular smooth muscle → arterial vasodilation
indication: hypertension adjunct

57

aliskiren (Tekturna)

MOA: direct renin inhibitor - inhibits renin = ↓ plasma renin activity as well as conversion of angiotensinogen I to angiotensin I
indication: hypertension, but avoid because it doesn't offer advantages compared with others, is expensive, and is a teratogen

58

nifedipine class

CCB

59

nicardipine (Cardene) class

CCB

60

verapamil class

CCB

61

diltiazem class

CCB

62

cholestyramine (Questran)

MOA: bile acid sequestrant - mostly ↓ LDL + may ↑ trigs
indication: lipid mgmt for angina tx

63

colesevelam (Welchol)

MOA: bile acid sequestrant - mostly ↓ LDL + may ↑ trigs
indication: lipid mgmt for angina tx

64

colestipol (Colestid)

MOA: bile acid sequestrant - mostly ↓ LDL + may ↑ trigs
indication: lipid mgmt for angina tx

65

gemfibrozil (Lopid)

MOA: fibrate
indication: lipid mgmt for angina tx

66

fenofibrate (Tricor)

MOA: fibrate
indication: lipid mgmt for angina tx

67

ezetimibe (Zetia)

MOA: cholesterol absorption inhibitor
indication: use in combo + statin to ↓ LDL