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buncha meds Flashcards

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1
Q

nimodipine (Nimotop)

MOA only

A

MOA: CCB - counters vasospasms by preventing Ca from entering smooth muscle cells + causing contraction (CVA)

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2
Q

ticlopidine (Ticlid)

A

MOA: anti-platelet

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3
Q

ticlopidine considerations

A

aka Ticlid

AE: assoc w agranulocytosis, thrombotic thrombocytopenia purpura, GI intolerance

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4
Q

pyridostigmine (Prostigmin)

A

MOA: anticholinesterase - block hydrolysis of ACh
indication: symptomatic improvement in myasthenia gravis

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5
Q

edrophonium (Tensilon)

A

MOA: ultra short-acting AChE inhbitor
indication: distinguish between myasthenia crisis & cholinergic crisis

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6
Q

carbidopa-levodopa (Sinemet)

A

MOA: increase available dopamine
indication: Parkinson’s Disease mgmt

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7
Q

amantadine (Symmetryl)

A

MOA: increase available dopamine
indication: Parkinson’s Disease mgmt

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8
Q

pramipexole (Mirapex)

A

MOA: increase available dopamine
indication: Parkinson’s Disease mgmt

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9
Q

ropinirole (Requip)

A

MOA: increase available dopamine
indication: Parkinson’s Disease mgmt

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10
Q

benztropine (Cogentin)

A

MOA: anticholinergic (alleviate tremor, rigidity)
indication: Parkinson’s Disease mgmt

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11
Q

trihexyphenyldyl (Artane)

A

MOA: anticholinergic (alleviate tremor, rigidity)
indication: Parkinson’s Disease mgmt

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12
Q

donepezil (Aricept) = memory improvement

A

MOA: acetylcholinesterase inhibitor
indication: Alzheimer’s (specifically, memory improvement)

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13
Q

rivastigmine (Exelon)

A

MOA: acetylcholinesterase inhibitor
indication: Alzheimer’s

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14
Q

albuterol (Proventil)

A

MOA: short-acting beta-2 adrenergic agonist (SABA), bronchodilates
indication: asthma rescue, sx relief/breakthrough, or pre-exercise; or inpt mgmt

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15
Q

budesonide (Pulmicort)

A

MOA: inhaled corticosteroid
indication: daily maintenance tx for asthma + increase if sx persist

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16
Q

triamcinolone (Azmacort)

A

MOA: inhaled corticosteroid
indication: daily maintenance tx for asthma + increase if sx persist

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17
Q

salmeterol (Serevent)

A

MOA: long-acting beta-2 adrenergic agonist (LABA)
indication: persistent asthma symptoms

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18
Q

ipratropium bromide (Atrovent)

A

MOA: inhaled anticholinergic
indication: asthma adjunct for secretion mgmt, also inpt mgmt

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19
Q

montelukast (Singulair)

A

MOA: antileukotriene
indication: chronic asthma - stabilization

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20
Q

alupent

A

MOA: inhalation sympathomimetic
indication: inpt mgmt of asthma

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21
Q

methylprednisolone 60 - 125 mg IV

A

MOA: corticosteroid
indication: inpt mgmt of asthma for pts who do not respond to sympathomimetics

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22
Q

aqueous epinephrine 1:1000 0.1 - 0.5 mL SQ

A

MOA: parenteral sympathomimetic
indication: asthma tx for inpt unable to cooperate

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23
Q

TB drug doses

A

Rifampin 600 mg
Isoniazid 300 mg
Pyrazinamide 1.5 - 2.0 g
Ethambutol 15 mg/kg

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24
Q

hydrocodone-APAP: generic for which 2 brands

A

Vicodin, Lortab

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25
amitriptyline (Elavil) class x2
antidepressant & neuropathic pain
26
sumatriptan (Imitrex)
MOA: triptan, 5-HT agonist uses: acute migraine
27
acetazolamide (Diamox)
MOA: carbonic anhydrase inhibitor, inhibits renal tubule H+ excretion (increases Na, K, bicarb, H2O excretion) producing alkaline diuresis uses: metabolic alkalosis
28
dantrolene sodium (Dantrium) is a treatment for
Serotonin Syndrome
29
diazepam
Valium
30
lorazepam
Ativan
31
midazolam
Versed
32
butorphanol (Stadol) use
opioid toxicity reversal
33
flumazenil (Romazicon) use
benzo toxicity reversal
34
calcineurin inhibitors x2
tacrolimus (Prograft) cyclosporine can use for transplant rejection prophylaxis
35
antimetabolites x 2
``` azathioprine (Imuran) mycophenolate mofetil (Cellcept) ``` can use for transplant rejection prophylaxis
36
glipizide (Glucotrol)
MOA: sulfonylurea - stimulate pancreas to release more insulin indication: diabetic oral agent
37
glyburide (Diabeta)
MOA: sulfonylurea - stimulate pancreas to release more insulin indication: diabetic oral agent
38
glimepiride (Amaryl)
MOA: sulfonylurea - stimulate pancreas to release more insulin indication: diabetic oral agent
39
acarbose (Precose)
MOA: alpha-glucosidase inhibitor - bind to disaccharidases more readily than sucrose, therefore less glucose absorbed by gut indication: oral antidiabetic
40
miglitol (Glyset)
MOA: alpha-glucosidase inhibitor - bind to disaccharidases more readily than sucrose, therefore less glucose absorbed by gut indication: oral antidiabetic
41
rosiglitazone maleate (Avandia)
MOA: "glitazone" - decrease gluconeogenesis indication: oral antidiabetic
42
pioglitazone hydrochloride (Actos)
MOA: "glitazone" - decrease gluconeogenesis indication: oral antidiabetic
43
repaglinide (Prandin)
MOA: non-sulfonylurea insulin release stimulator - rapidly abs from intestine & mimics effect of rapid-acting insulin indication: indication: oral antidiabetic
44
nateglinide (Starlix)
MOA: non-sulfonylurea insulin release stimulator - rapidly abs from intestine & mimics effect of rapid-acting insulin indication: indication: oral antidiabetic
45
ACE inhibitor MOA*
block RAAS system @ angiotensin II
46
thiazide diuretics MOA*
⊣ reabs Na + Cl in distal tubule → ↑ urinary excretion Na + H2O Direct arteriolar vasodilation.
47
loop diuretics MOA*
K EXCRETED ⊣ reabs Na + Cl in proximal + distal tubules + loop of Henle (Na-K-Cl co-transporter = K reabs) interferes with Cl-binding cotransport system, → ↑ excretion Na, H2O, Ca, Mg, Cl
48
spironolactone MOA*
K SPARED competes with aldosterone @ distal tubule receptors ↑ Na Cl + H2O excretion while conserving K + H
49
diltiazem class
CCB
50
amlodipine class
CCB
51
prazosin (Minipress)
MOA: alpha-1 antagonist - causes vasodilation indication: BPH, htn adjunct
52
terazosin (Hytrin)
MOA: alpha-1 antagonist - causes vasodilation indication: BPH, htn adjunct
53
doxazosin (Cardura)
MOA: alpha-1 antagonist - causes vasodilation indication: BPH, htn adjunct
54
clonidine (Catapres)
MOA: central alpha-2 agonist - prevents vasoconstriction, causes vasodilation, negative chronotrope indication: hypertension adjunct
55
methyldopa (Aldomet)
MOA: central alpha-2 agonist - prevents vasoconstriction, causes vasodilation, negative chronotrope indication: hypertension adjunct
56
minodixil (Loniten)
MOA: arterial vasodilator - directly relaxes vascular smooth muscle → arterial vasodilation indication: hypertension adjunct
57
aliskiren (Tekturna)
MOA: direct renin inhibitor - inhibits renin = ↓ plasma renin activity as well as conversion of angiotensinogen I to angiotensin I indication: hypertension, but avoid because it doesn't offer advantages compared with others, is expensive, and is a teratogen
58
nifedipine class
CCB
59
nicardipine (Cardene) class
CCB
60
verapamil class
CCB
61
diltiazem class
CCB
62
cholestyramine (Questran)
MOA: bile acid sequestrant - mostly ↓ LDL + may ↑ trigs indication: lipid mgmt for angina tx
63
colesevelam (Welchol)
MOA: bile acid sequestrant - mostly ↓ LDL + may ↑ trigs indication: lipid mgmt for angina tx
64
colestipol (Colestid)
MOA: bile acid sequestrant - mostly ↓ LDL + may ↑ trigs indication: lipid mgmt for angina tx
65
gemfibrozil (Lopid)
MOA: fibrate indication: lipid mgmt for angina tx
66
fenofibrate (Tricor)
MOA: fibrate indication: lipid mgmt for angina tx
67
ezetimibe (Zetia)
MOA: cholesterol absorption inhibitor indication: use in combo + statin to ↓ LDL

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