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Flashcards in Campylobacter Deck (18):
0

Microscopy characteristics of Campylobacter?

Spiral
Gram-negative
Bacilli
Highly motile (darting movement)

1

Name of a Campylobacter?

Campylobacter jejuni.

2

How is Campylobacter spread?

Faecal-oral route.

3

How is Campylobacter related to Diarrhoea?

It is the leading cause of bacterial Diarrhoea.

4

What is Campylobacter a cause of?

Gastroenteritis.
Colitis.

5

What kind of media does one need to grow Campylobacter?

Blood-containing media.

6

Where does one find Campylobacter in the environment?

Wild or domestic animals (including birds)

7

How can one acquire Campylobacter?

Contaminated food (undercooked poultry)
Direct transmission (puppies and kittens)
Faecal-oral route
Unpasteurized milk
Unchlorinated water

8

Is campylobacter a cause of travellers Diarrhoea? Why?

Yes. High prevalence in developing countries.

9

What does Campylobacter jejuni cause?

Acute enterocolitis.

10

Symptoms of C.jejuni infection?

Diarrhoea - watery to frankly dysenteric
Malaise
Fever
Colic

11

What would you see if you had to perform a laparotomy on someone infected with C.jejuni?

Ileitis
Mesenteric adenitis

12

Can Campylobacter cause serious life-threatening illness?

Yes.
In the immunocompromised, elderly and neonates.

13

What syndrome can be a complication of Campylobacter infection?

Guillain-Barre Syndrome

14

What is Guillain-Barr Syndrome?

Autoimmune reaction > ab's to Campylobacter target nervous tissue > ascending paralysis
*respiratory dysfunction?
*molecular mimicry

15

How can one diagnose a Campylobacter infection?

Culture - use faeces or blood
Gastric biopsy

16

Treatment of a Campylobacter infection?

Rehydration
Antibiotics
*diarrhoea is usually self-limiting so antibiotics not normally given

17

What antibiotics can be used to treat a Campylobacter infection?

Erythromycin
Quinolones