Cancer Flashcards

1
Q

Treatment of chronic myeloid leukaemia?

A

Imatinib (Tyrosine Kinase Inhibitor)

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2
Q

What on a blood test could indicated lung cancer?

A

Raised platelets

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3
Q

SCLC + lef weakness makes you think what?

A

Lambert Eaton syndrome

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4
Q

HPV 6 & 11 bad or good?

A

Good (in relativity)
Only cause genital warts

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5
Q

Cancerous HPV types?

A

16 & 18

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6
Q

WHat type of cancer is schistosomiasis a RF for?

A

SCC of the bladder

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7
Q

Pancreatic cancer invgX?

A

High res CT

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8
Q

Blood film finding of CLL?

A

Smudge cells

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9
Q

The is a greater/lesser risk if ovulation is not suppressed for ovarian cancer?

A

Greater

-Early menarche
-Late menopause
-Obesity
-Hormone replacement therapy

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10
Q

What can NSAIDs increase the risk of in patients with chicken pox?

A

Nec Fasciitis

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11
Q

What illicit drug can increase risk of serotonin syndrome in SSRI users?

A

MDMA

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12
Q

What can be prevented by prescribing isoniazid and pyridoxine together?

A

Peripheral neuropathy

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13
Q

Urge incontinence treatment in elderly people to avoid them becoming confused?

A

Mirabegron instead of oxybutynin

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14
Q

Treatment of anaphylactoid reaction to N-acetylcysteine?

A

Stop infusion and restart at lower rate

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15
Q

Peripheral blood smear showing RBC agglutination is indicative of what disease?

A

Mycoplasma pneumoniae

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16
Q

What ABG can heroin overdose produce?

A

Resp depression > hypoventilation >

resp acidosis

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17
Q

Oesophageal ulcers are probably caused by?

A

Alendronic acid

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18
Q

Whooping cough treatment in kids?

A

Oral azithromycin

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19
Q

Rifampicin SEs?

A

Hepatitis
Orange secretions
Flu-like symptoms

(Rifampicin is potent liver enzyme inducer)

20
Q

SEs of isoniazid?

A

Peripheral neuropathy
Hepatitis
Agranulocytosis

Liver enzyme inhibitor

21
Q

SEs of pyrazinamide?

A

Hyperuricaemia causing gout
Arthralgia, myalgia
Hepatitis

22
Q

SEs of ethambutol?

A

Optic neuritis

23
Q

Haematuria means what test is required?

A

MSU

24
Q

In pregnancy if patient has cellulitis and is penicillin allergic what do you want to prescribe her?

A

Erythromycin

25
Q

Life threatening C Diff treatment?

A

ORAL Vancomycin
IV metronidazole

26
Q

Name of criteria for liver transplantation in paracetamol liver failure? + criteria

A

King’s College Hospital Criteria

Arterial pH <7.3, 24 hours after ingestion

or all of following:
- PT time >100secs
-Creatinine >300umol/l
-Grade III or IV encephalopathy

27
Q

Paediatric BLS: if no signs of breathing on initial assessment what do you do?

A

5 rescue breaths

28
Q

Continuous IECOPD treatment?

A

Azithro once-daily

29
Q

What artery bleed is most likely to cause leg weakness without face or speech impairment?

A

Anterior cerebral artery

30
Q

Compressions for kids rate?

A

100-120

31
Q

Where is this stroke?

-Sudden onset vertigo and vomiting
-Ipsilateral facial paralysis
-Deafness

A

Anterior inferior cerebellar artery

32
Q

What type of diagnoses is this?
Hypodense (dark) crescenteric collection around convexity of brain?

A

Chronic subdural haematoma

33
Q

Which conditions have postural hypotension with compensatory tachycardia?

A

4D’s
-Deconditioning
-Dysfunctional heart: aortic stenosis
-Dehydration, dialysis
-Drugs: anti-anginals anti-psychotics, tamsulosin, anti-parkinsonian drugs

34
Q

Diagnosis of legionella

A

Urinary antigen test

34
Q

What lobe of brain causes lip smacking, epigastric aura etc?

A

Temporal lobe

34
Q

What do frontal lobe seizures present with?

A

Jacksonian march (paraesthesia distal peripheries proximally)
Todd’s paralysis

35
Q

Salicylate poisoning blood gases?

A

Resp alkalosis -> metabolic acidosis

35
Q

Contralateral homonymous hemianopia with macular sparing + visual agnosia?

A

Posterior cerebral artery stroke

36
Q

Where to check pulses in an infant?

A

Brachial or femoral

37
Q

Drugs to stop in AKI?

A

CANADA

Contrast media
ACEIs
NSAIDs
AMinoglycosides
Diuretics
ARBs

38
Q

Addison’s disease blood gas?

A

Hyperkalaemic metabolic acidosis

39
Q

Common consequence of SAH?

A

SIADH

40
Q

What type of lesions is staph aureus pneumoniae assoc with?

A

Cavitating lesions

41
Q

SAH comp?

A

Hyponatraemia

42
Q

Prophylaxis of contacts of patient’s who have meingococcal meningitis?

A

Oral rifampicin
Oral ciprofloxacin

43
Q
A