GP Flashcards

1
Q

Cauda Equina syndrome symptoms?

A

Increasing backpain
Bilateral sciatica
Sensory loss in lumbosacral distribution
Flaccid, weakened lower limbs
Reduced reflexes
Urinary symptoms

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2
Q

Presentation of
-Demyelination
-MND
-Cerebral tumour
-Syrinx
-Subacute combined cord degeneration

A

Spastic paraparesis

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3
Q

6 causes of cauda equina syndrome?

A

Bony mets
Myeloma
Epidural abscess
Disc prolapse
Epidural haematoma
Primary sacral tumour

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4
Q

Further management of cauda equina syndrome?

A

Arrange urgent spinal surgical admission that day

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5
Q

Differentiating between compression of cauda equina and cord?

A

CE: Loss of reflexes, flaccid paralysis
CC: Spastic paralysis, brisk reflexes

Both: sensory/power loss

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6
Q

S1 supplies which sensory dermatome?

A

Sole of foot

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7
Q

L2 Supplies which sensory dermatome?

A

Upper anterior thigh

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8
Q

L1 supplies which sensory dermatome?

A

Groin

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9
Q

L3 supplies which sensory dermatome?

A

Buttock

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10
Q

L4 supplies what sensory dermatome?

A

Calf

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11
Q

Someone has just been diagnosed with diabetes what is your first port of call for treatment?

A

Lifestyle advice:
- Diet
-Physical activity
Screening for diabetic complications

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12
Q

What is 1st line treatment for T2DM and why?

A

Metformin
-Weight neutral
-Good glucose lowering efficacy

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13
Q

What must be monitored before and during metformin use?

A

Renal function

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14
Q

Con of pioglitazone and gliclazide?

A

Weight gain

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15
Q

Metformin SEs?

A

Diarrhoea (GI upset)

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16
Q

Management of migraines?

A

Acute: Rizatriptan, diclofenac
Prophylaxis: Propranolol, amitriptyline, topirmate

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17
Q

Symptoms that would be seen in gastroenteritis?

A

-Streak of blood in vomit
-Intermittent abdo pain
-Blood in stool
-Mucus in stool

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18
Q

Treatment of gastroenteritis?

A

-Drink reg fluids
-Take paracetamol for abdo pains
-Observe hygiene measures like wash hands, separate towels etc

Consider supplementing fluid intake with rehydration salrs in adults at increased risk (>60 y/o, frail, comorbidities where dehyrdration would be problematic (CVS issues/thrombotic tendencies)

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19
Q

Treatment of choice for Tonsilitis?

A

Penicillin V

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20
Q

Patient wants tests as her father just died of MI aged 39, what blood test do you do?

A

Fasting lipid profile

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21
Q

Good cholesterol?

A

HDL

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22
Q

LDL is good or bad?

A

BAD cholesterol

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23
Q

Treatment of high cholesterol?

A

Statins
Ezetimibe
Fenofibrate

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24
Q

Common SE of statins?

A

Asthenis
GI disturbance
Headache

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25
Q

Other possible causes of hypercholesterolaemia?

A

-Obesity
-Chronic renal failure
-Alcohol XS
-Anorexia nervosa
-Uncontrolled hypothyroidism

If not these: familial

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26
Q

Mechanism of statins?

A

HMG CoA reductase inhibitors

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27
Q

Statins and pregnancy?

A

Avoid
Discontinue 3 months before attempting conception

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28
Q

2 things which increase exposure to statins?

A

-Grapefruit juice
-Clarithromycin (monitor rhabdomyolysis if on)

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29
Q

Definition of septicaemia?

A

Multiplication of bacteria in the bloodstream

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30
Q

Definition of bacteraemia?

A

Presence of bacteria in bloodstream

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31
Q

Treatment of meningococcal septicaemia patient while waiting for an ambulance?

A

Lying them down + high flow O2
IV/IM benzylpenicillin

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32
Q

Reporting and meningococcal diseases?

A

Always report

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33
Q

Differential diagnoses for maculo-papular rash?

A

-Parovirus B19
-Drug hypersensitivity
-Measles
-EBV

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34
Q

What is a maculopapular rash, beginning behind ears and spreading to the trunk pathognomonic of?

A

Measles

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35
Q

Symptoms of measles?

A

-High fever
-Incubation period 10-12 days
-Koplik spots
-Maculopapular rash
-Cough
-Coryza
-Irritabililty
-Red eyes

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36
Q

Incubation period of measles?

A

10-12 days

37
Q

When are measles patients infectious from?

A

4 days before onset of rash to 5 days after it appears

38
Q

Complications of measles for a pregnant woman?

A

Encephalitis
Subacute sclerosing panencephalitis
Bronchopneumonia
Stillbirth

39
Q

What disease has the complication of infective endocarditis?

A

Rheumatic fever

40
Q

Dukes criteria A-D?

A

A: Bowel wall
B: Through wall but not nodes
C: Regional nodes
D: Distant mets present

41
Q

Chlamydia infection treatment?

A

Doxycycline orally

42
Q

Signs of RA in hands?

A

Swan neck deformity
Swelling of MCPs
Synovial swelling
Boutonniere’’s deformity
Ulnar deviation

43
Q

Hand deformities seen in OA?

A

Heberden’s nodes (DIPs)
Bouchard nodes (PIPs)

44
Q

Serological investigations for RA?

A

Anti-CCP (80% of people with RA)
ANA- Non-specific for AI conditions
RF- 60-70% of people with Rheumatoid arthritis

45
Q

Examples of DMARDs?

A

Methotrexate
Hydroxychloroquine
Sulphasalazine

46
Q

Extra-articular presentations of RA?

A

Scleritis
Pulmonary Fibrosis
CVD
Amyloidosis

(chronic inflammatory connective tissue disorder so extra manifestations are along that vibe too)

47
Q

First line for uncomplicated lower UTI?

A

Trimethoprim 200g BD 3 days
OR
Nuturofurantoin 100mg MR BD 3 days (GFR <40)

48
Q

Causes of recurrent UTIs?

A

Renal stones
Diabetes
Sexual intercourse

49
Q

Drugs assoc with dyspepsia?

A

Calcium antagonists
Nitrates
Theiphylines
Bisphosphonates
Corticosteroids
NSAIDs

50
Q

Normal Hb levels?

A

120-155

51
Q

Normal WCC?

A

4-11 X 10>9

52
Q

Normal Na+?

A

136-145

53
Q

Normal K+?

A

3.5-5.1

54
Q

Normal Urea?

A

1.7-8.3

55
Q

Tennis elbow AKA?

A

Lateral epicondylitis

56
Q

What muscle does tennis elbow affect?

A

Extensor muscle attachment into lateral epicondyle of humerus

57
Q

Clinical presentation of tennis elbow?

A

-Localised point tenderness on palpation over and/or distal to lateral epicondyle
-Painful Resisted Middle Finger Extension muscle test
-Weakened grip strength
-Full active and Passive Elbow ROM

58
Q

Phalen’s test diagnoses what?

A

Carpal Tunnel Syndrome

59
Q

4 dying meds?

A

Midazolam: agitation
Morphine Sulfate: Pain
Cyclizine: N/V
Glycopyrronium: resp secretions

60
Q

Treatment of mastitis?

A

10-14 days flucloxacillin

61
Q

Infected insect bite treatment?

A

Fluclox 500-1000mg x2 daily 5-7 days
Clarothromycin 500mg twice daily 5-7 days
Doxycycline 200mg 1st day, 100mg once daily 5-7 days total
Erythro (pregnant) 500mg x4 daily for 5-7 days

62
Q

Platelet normal values?

A

150-450

63
Q

MCV normal?

A

76-100

64
Q

HHV - 8 is what virus?

A

Kaposi Sarcoma- neoplastic skin lesions

65
Q

HHV-5 is commonly called?

A

Cytomegalovirus

66
Q

HHV-4 called?

A

Epstein Barr Mononucleosis

67
Q

HHV-3 called?

A

Varicella Zoster - Chicken Pox

68
Q

hhv-1 called?

A

Herpes simplex- cold sore

69
Q

HHV-2 called?

A

Herpes Simplex Virus coldsore

70
Q

Prescribe for paediatric meningitis possibility?

A

BENPENTEN
Benzylpenicillan
1-9 years: 600mg
>10 : 1200mg
<1: 300mg

71
Q

Normal bilirubin values?

A

0-21

72
Q

Normal ALP?

A

40-129

73
Q

Normal AST?

A

0-40

74
Q

Normal GGT?

A

10-71

75
Q

Normal CRP?

A

<5

76
Q

Normal ESR?

A

0-15

77
Q

Treatment of Scabies?

A

Permethrin 5% cream
Whole body, not scalp and face.

78
Q

Pathophysiology of venous ulcer formation?

A

Chronic venous insufficiency (CVI)
Venous HT
Poor oxygen diffusion
Retrograde Flow

79
Q

What is keratoacanthoma?

A

Rapidly growing skin lesion
Distinguishable from manvasive squamous cell carcinoma histologically
Doesn’t invade or metastatsize
Grow rapidly (6 weeks)

80
Q

Chronic gout treatment?

A

Urate Lowering Treatment: Allopurinol 100mg OD

Requires regular blood testing to chec urate levels, initial LFT, U&E check

81
Q

Diagnostic features of pseudogout?

A

-Joint aspiration would show calcium pyrophosphate dihydrate (CPPD) crystals
-Knee x-ray would show calcification of articular cartilage

82
Q

Colchicine treatment for acute gout?

A

500 ug QDS 2-3 days

83
Q

Licensed prophylactic dose for chronic gout when starting allopurinol?

A

500 ug of colchicine BD up to 6 months as prophylaxis whilst starting allopurinol

84
Q

Treatment of lice?

A

Dimeticone 4%
Malathion is 2nd line

84
Q
A
84
Q
A
84
Q
A
85
Q

Pneumonic for remembering sick day drugs?

A

those DAMN Drugs
-Diuretics
-ACE Inhibitors
-Metformin
-NSAIDs

86
Q
A