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Flashcards in Cancer Deck (13):
1

Important factors in a cancer history?

Personal facts - age and gender

Diagnosis - Grade and stage

Treatments given in order

Most recent treatment

Current problem

PMH, DH, FH, SH

ICE

2

What are the different treatment options for cancer (how is it split up between the different stages of cancer)

One organ:

- Surgery
- Radiotherapy
- Ablation

Metastatic

- Chemo
- Hormone therapy
- Immunotherapy
- Debulking surgery

Curable with systemic chemotherapy

- Chemo

3

Grade and stage?

Stage - how far

Grade - how undifferentiated

4

What is adjuvant chemotherapy?

Chemotherapy that is given when it is suspected the cancer will return.

5

S/Es of radiotherapy?

Fatigue, localised soreness, pulmonary fibrosis

6

Examples of chemosensitive cancers?

Choriocarcinoma

Testicular cancer

Leukaemia

Some Lymphomas

Some Sarcomas

7

Reasons why chemotherapy doesn't work?

Resistant to that chemotherapy

Can't tolerate the chemo

Sanctuary sights - chemo can't reach it e.g.

8

Common side effects of chemo?

Think of areas with constantly dividing cells:

Neutropaenic sepsis

Hair loss
Bone marrow - Anaemia, thrombocytopaenia,
Infertility
Nausea
Diarrhoea

9

What is neutropaenic sepsis? Treatment (SGH)

Reduction in production of white cells

10

Implications for cerebellar metastases on the patients life?

Cannot drive - at risk of seizures

11

Triple assessment for breast cancer diagnosis?

History

Imaging - mommogram, MRI

Biopsy

12

Therapies used to treat breast cancer?

Local therapies:

Surgery
Radiotherapy

Systemic therapy:

Chemotherapy
Bisphosphonates
Hormone therapy - Tamoxifen
Biological therapies - Herceptin

13

Factors that govern the choice of systemic treatment for advanced breast cancer. (reoccurence)

Tumour related factors
- Prognosis
- Response to prior treatment
- Tumour biomarkers
- Disease free interval

Patient related factors
- Physiological fitness
- Menopausal status
- Comorbidities
- Tolerance of prior treatment
- Patient preferences