Flashcards in Infective Endocarditis Deck (15):
Unspecific symptoms of Infective endocarditis?
Specific Symptoms of infective endocarditis?
Definition of infective endocarditis?
Infection of the endocardial surface of the heart, most commonly involving the cardiac valves.
Key investigation to perform for suspected infective endocarditis?
Infective endocarditis R/Fs?
PMH of IE
Valvular heart disease
Long term indwelling catheters
Poor dental hygiene
Intravenous drug user (IVDU)
Events that lead to the development of infective endocarditis?
1. Endocardial damage
2. Microbes in the bloodstream (Dental cleaning, LRTI, dermatitis, catheters)
3. Adherence + proliferation of microbes in the safety of a protective fibrin clot
Complications of infective endocarditis?
Aortic root abscess
AKI (immune complex deposition)
Vessel infarctions to important organs
Types of Echocardiogram?
Outside - Transthoracic echocrdiogram (TTE)
Inside - Transoesophageal echcardiogram (TOE)
Surgical interventions in IE?
Debridement of infected tissue
Closure of cardiac defects
Aortic homografts useful for aortic root abscess
Patient mortality of IE?
Criteria for IE diagnosis?
- Positive blood culture
- Abnormal echo
- New valvular regurge
Immediate management of IE?
What do you need to monitor in IE?
Signs of failing antibiotic treatment
Monitor PR interval
Male/Female more likely to have IE?