Canine Distemper Flashcards
(14 cards)
What genus does distemper belong to?
Morbillivirus
Besides dogs, which other species is highly susceptible to distemper virus?
Ferrets
Is the distemper and enveloped or non-enveloped virus? Does this mean it last long or short amount of time in the environment?
Enveloped, short amount of time (1 day at room temperature)
What cells are initially infected with distemper virus? Where are they located?
Monocytes of the upper respiratory tract
Viral distemper HA binds to a molecule on the surface of host cells, which allows entry into the cell. What is the name of this molecule?
signaling lymphocytic activation molecule (SLAM)
In particular, which lymphocytic cell line is destroyed from distemper virus?
CD4+ T cells
CDV is shed in all secretions as early as _____ after infection, before the onset of clinical signs. Shedding can continue for as long as _____, but usually resolves after 1-2 weeks.
5 days
3-4 months
What percentage of dogs develop CNS signs of distemper?
30%
How does distemper tend to affect neurons?
Demyelination
Can distemper cause KCS?
Yes, via damage to lacrimal gland
Secondary infections are common with distemper. These most commonly localize to which part of the body and what is a common copathogen?
Respiratory, bordetella
The canine infectious respiratory disease complex (CIRDC), formally “kennel cough” contains 7 viruses, which are?
Canine herpesvirus
Canine adenovirus
Canine distemper virus
Canine parainfluenza
Canine pneumovirus
Canine respiratory coronavirus
Canine influenza virus
Of the 7 viral causes of CIRDC, which one is non-enveloped and can live in the environment for long periods of time?
Canine adenovirus
Which of the CIRDC viruses has a strain that can causes infectious hepatitis in dogs?
Adenovirus (CAD-1). The respiratory strain is CAD-2 and the vaccine works for both
