Related to steroids, CPPP nucleus
CARDIAC GLYCOSIDES
CARDIAC GLYCOSIDES Sugar component is attached on the
3rd position of the CPPP nucleus
2 aglycones
cardenolides and (2) bufadienolides
An Arrythmogenic
DIGITALIS
Sources of digitalis
Foxglove (D. Purpurea) Grecian foxglove (D. lanata)
Digoxin from
D. lanata
- It is polar because of the –OH group in the structure
* Easily eliminated, therefore, SHORT ACTING
DIGOXIN
digitoxin from
D. Purpurea
It is used for rapid digitalization
DESLANOSIDE
Lily of the Valley
Convallaria
Convallaria from
Convallaria majalis
Convallaria active component
Convallotoxin
AKA: Black Indian hemp, Dog Bane
Apocynum
Apocynum from
Apocynum cannabinum
active cardiac glycoside of apocynum
Cymarin
Adonis is aka
Pheasant’s eye
Adonis from
Adonis vernalis
Adonis constituents
ADONITOXIN, CYMARIN, K- STROPHANTIN
CACTUS GRANDIFLORUS aka
Night Blooming Cereus
CACTUS GRANDIFLORUS from
Selenicereus grandifloras
Black hellebore
Christmas Rose
Black hellebore from
Helleborous niger
Black hellebore constituents
Hellebrin
glycosidal, cardiac stimulant (inotropic)
Black
alkaloidal, cardiac depressant
Green and white
STROPHANTHUS is from
S. kombe and S. hispidus
component of strophantus
K. stophantoside
3rd most important glycoside available in the market
G. strophantin (ouabain)
From Urginea maritima
SQUILL OR SQUILL BULB
Component of SQUILL OR SQUILL BULB
SCILLAREN- A
SCILLAREN- A converted to
scillarenin
From Nerium oleander
Adelfa
Genocide in Sri lanka
Adelfa