Cardio Cardiac/Vascular Tumors + Vasculitis Flashcards Preview

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Flashcards in Cardio Cardiac/Vascular Tumors + Vasculitis Deck (32)
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1

Cystic hygroma

what is it?
association?

vascular tumor - cavernous lymphangioma of the neck

Turner syndrome (XO)

2

Angiosarcoma

causes?

vascular tumor of the H&N and breast areas

causes
- post-radiation therapy
- vinyl chloride
- arsenic

3

Lymphangiosarcoma

association?

lymphatic malignancy associated with persistent lymphaedema, usually occurs post-radical mastectomy

4

Cherry hemangioma

vascular tumor - benign capillary hemangioma of the ELDERLY. does not regress, but rather increases with age

5

Strawberry hemangioma

vascular tumor - benign capillary hemangioma of the INFANCY. Regresses with age

6

Glomus tumor

derived from? features?

vascular tumor that arises from modified smooth muscle cells of glomus body

benign, painful, red-blue tumors underneath fingernails

7

Kaposi's sarcoma

associations?

vascular tumor - associated with HHV8 and HIV

8

Pyogenic granuloma

causes? features?

vascular tumor caused by trauma and pregnancy; can ulcerate and bleed

9

Bacillary angiomatosis

associations?

vascular tumor - benign capillary skin papules

associated with AIDs, bartonella henselae infections

10

Buerger's disease
type of vasculitis?
pathology?

type: medium-vessel vasculitis
pathology: segmental thrombosing vasculitis

11

Churg-Strauss syndrome
type of vasculitis?
pathology?

type: small-vessel vasculitis
pathology: granuomatous + vasculitis with EOSINOPHILIA, elevated IgE, p-ANCA

12

Granulomatosis with polyangiitis (Wegener's)
type of vasculitis?
pathology?

type: small-vessel vasculitis
pathology:
- necrotizing granulomas in lung+upper airway
- necrotizing vasculitis
- necrotizing glomerulonephritis
- c-ANCA

13

Henoch-Schonlein purpura
type of vasculitis?
pathology?

type: small-vessel vasculitis
pathology: vasculitis due to IgA complex deposition

14

Kawasaki disease
type of vasculitis?
pathology?

type: medium-vessel vasculitis
pathology: coronary artery aneurysms -> can rupture leading to infarction

15

microscopic polyangitis
type of vasculitis?
pathology?

type: small-vessel vasculitis
pathology: necrotizing vasculitis (lungs, kidney, skin - palpable purpura), p-ANCA

16

Polyarteritis nodosa
type of vasculitis?
pathology?

type: medium-vessel vasculitis
pathology: fibrinoid necrosis (immune complex mediated) w/ transmural inflammation) of renal + visceral arteries

17

Takayasu's arteritis
type of vasculitis?
pathology?

type: large-vessel vasculitis
pathology: granulomatous inflammation of aortic arch + proximal great vessels (->luminal narrowing), elevated ESR

18

Temporal (giant cell) arteritis
type of vasculitis?
pathology?

type: large-vessel vasculitis
pathology: focal granulomatous, carotid + cranial arteries, elevated ESR

19

Buerger's disease
signs & sx?
treatment?

signs/symptoms: M smokers -> Raynaud's -> digit gangrene -> autoamputation
treatment: smoking cessation

20

Churg-Strauss syndrome
signs & sx?

signs/symptoms: asthma, palpable purpura, wrist/foot drop, glomerulonephritis

21

Granulomatosis with polyangiitis (Wegener's)
signs & sx?
treatment?

signs/symptoms:
- chronic sinusitis
- nasal septal perforation
- hemoptysis/cough
-hematuria w/ RBC casts
treatment: prednisone, cyclophosphamide

22

Henoch-Schonlein purpura
signs & sx?
treatment?

signs/symptoms: child with URI --> later develops palpable purpura on buttocks, arthalgia, abdominal pain w/ melena, glomerulonephritis

treatment: supportive (usually recover spontaneously)

23

Kawasaki disease
signs & sx?
treatment?

signs/symptoms: young child w/
- fever
- cervical lymphadenopathy
- conjunctival injection
- strawberry tongue
- rash on hands/feet
- desquamating rash

treatment: IVIG, Aspirin

24

microscopic polyangitis
signs & sx?
treatment?

signs/symptoms: lungs, kidneys, glomerulonephritis, palpable purpura
treatment: prednisone, cyclophosphamide

25

Polyarteritis nodosa
association?
signs and sx?
treatment?

association: HBV
signs/symptoms: HTN (renal disease, neurological ∆, cutaneous eruptions)
treatment: prednisone, cyclophosphamide

26

Temporal (giant cell) arteritis
signs & sx?
treatment?
associations?

signs/symptoms: unilateral headache and jaw claudication --> blindness
treatment: high-dose prednisone
association: polymyalgia rheumatica

27

Takayasu's arteritis
signs & sx?
treatment?

signs/symptoms: asian F < 40 years, weak upper extremity pulses, fever, night sweats, arthritis
treatment: steroids

28

granulomatous vasculitis 4

Temporal (Giant cell)
Takayasu
Wegner's
Churg Strauss

29

thrombosing vasculitis

Buergers

30

Systemic vasculitis

Henoch Schoen purpura