Cardio Embryology + congenital tumors Flashcards Preview

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Flashcards in Cardio Embryology + congenital tumors Deck (76)
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1

Truncus arteriosus gives rise to

ascending aorta + pulmonary trunk

2

bulbus cordis gives rise to

smooth parts (outflow) tracts of L/R ventricles

3

primitive atria gives rise to

trabeculated part of L/R atria

4

primitive ventricle gives rise to

trabeculated part of L/R ventricles

5

primitive pulmonary vein gives rise to

smooth part of L atrium

6

L horn of sinus venosus (SV) gives rise to

coronary sinus - resides in the atrioventricular groove on the posterior aspect of the heart

7

R horn of sinus venosus (SV) gives rise to

smooth part of R atrium

8

R common cardinal vein and R anterior cardinal vein gives rise to

SVC

9

embryonic structures that give rise to smooth parts of the heart only

bulbus cordis - smooth parts (outflow) tracts of L/R ventricles
primitive pulmonary vein - smooth part of L atrium
R horn of sinus venosus (SV) - smooth part of R atrium

10

embryonic structures that give rise to trabeculated parts of the heart only

primitive atria - trabeculated part of L/R atria
primitive ventricle - trabeculated part of L/R ventricles

11

septum primum forms what

foramen secundum as it grows towards the endocardial cushions, thereby narrowing foramen primum

12

septum secundum forms what

forms foramen ovale as it covers most of foramen secundum

13

foramen ovale is comprised of these two structures

septum primum
septum secundum

14

ventricular septum is comprised of these two muscle types

smooth (upper) + muscular (lower) parts

15

what forms the aorticopulmonary septum? What does this go on to form?

What happens if this sequence malfunctions?

neural crest + endocardial cell migrations -> truncal + bulbar ridges spiral and fuse -> articopulmonary septum -> ascending aorta + pulmonary trunk

malfunction:
-> transposition of the great vessels
-> tetraology of fallot
-> persistent truncus arteriosus

16

aortic valve is derived from..

endocardial cushions

17

mitral valve derive from...

fused endocardial cushions of the AV canal

18

pulmonary valve is derived from..

endocardial cushions

19

tricuspid valve is derived from...

fused endocardial cushions of the AV canal

20

valves that derive from fused endocardial cushions of the AV canal...

mitral + tricuspid valves

21

valves that derive from endocardial cushions

aortic + pulmonary valves

22

fetal hemoglobin composition, HgF

α2γ2

also due to β thalassemia

23

adult hemoglobin composition, HgA1 (major)

α2β2

24

HgH composition

β4, due to alpha-thalassemia (when 3 copies are deleted, causes hemolysis with hepatosplenomeagly)

25

adult hemoglobin composition, HgA2 (minor)

α2δ2

26

Hemoglobin Barts

γ4, due to alpha-thalassemia (when all 4 copies are deleted; causes hydrops fetalis)

27

ductus venosus connects?

umbilical vein (O2 blood) to IVC; bypasses the liver

28

patent ductus arteriosus connects?

pulmonary artery to aorta

29

foramen ovale connects

L/R atria

30

fossa ovalis was once the....

foramen ovale