Receptors & signaling molecules Flashcards by Jullet Han

Signaling pathway of: PTH

cAMP

“FLAT ChAMP” likes to cAMP

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Signaling pathway of: glucagon

cAMP

“FLAT ChAMP” likes to cAMP

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Signaling pathway of: Estrogen

steroid (intracellular) receptor

“VETTT CAP”

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Signaling pathway of: Progesterone

steroid (intracellular) receptor

“VETTT CAP”

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Signaling pathway of: FGF

Intrinsic tyrosine kinase (TK), MAP kinase pathways

“growth factors” - in order to grow, you need insulin, growth factors, and a good MAP

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what receptors activate Adenylyl cyclase? inhibits?

activate: Receptor Gs (β1, β2, D1, H2, V2)
inhibit: Gi (M2, α2, D2)

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Signaling pathway of: Histamine

IP3

“A TOGA is HH-IP3 (hippy)”

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G protein class: q

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G protein class: i

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Signaling pathway of: CRH

cAMP

“FLAT ChAMP” likes to cAMP

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Signaling pathway of: ADH (V1)

IP3

“A TOGA is HH-IP3 (hippy)”

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Signaling pathway of: IL-6

Receptor-ASSOCIATED tyrosine kinase pathways (ie JAK/STAT)

“JAK the PIG does not like camp fires because it can get killed STAT”
^{know that PIG signals thorugh a separate pathway than FLAT}

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Signaling pathway of: epinephrine

cAMP

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Signaling pathway of: ANP

cGMP

“vasodilators”

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Signaling pathway of: IL-2

Receptor-ASSOCIATED tyrosine kinase pathways (JAK/STAT)

“JAK the PIG does not like camp fires because it can get killed STAT”
^{<span>know that PIG signals thorugh a separate pathway than FLAT</span>}

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Signaling pathway of: GH

Receptor-ASSOCIATED tyrosine kinase pathways (JAK/STAT)

“JAK the PIG does not like camp fires because it can get killed STAT”
know that PIG signals thorugh a separate pathway than FLAT

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Signaling pathway of: IL-8

Receptor-ASSOCIATED tyrosine kinase pathways (JAK/STAT)

“JAK the PIG does not like camp fires because it can get killed STAT”
know that PIG signals thorugh a separate pathway than FLAT

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Signaling pathway of: Angiotensin II

IP3

“A TOGA is HH-IP3 (hippy)”

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Signaling pathway of: GHRH

cAMP

“FLAT ChAMP” likes to cAMP

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Signaling pathway of: Cortisol

steroid (intracellular) receptor

“VETTT CAP”

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Signaling pathway of: Testosterone

steroid (intracellular) receptor

“VETTT CAP”

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β1

G protein class: s

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Signaling pathway of: ACTH

cAMP

“FLAT ChAMP”

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Receptors that signal through Gi?

Study These Flashcards

Gi (M2, α2, D2) - decrease cAMP

Signaling pathway of: TSH

cAMP "FLAT ChAMP" likes to cAMP

α2

G protein class: i

G protein class: s

Signaling pathway of: NO (EDRF)

cGMP "vasodilators"

Signaling pathway of: T3/T4

steroid (intracellular) receptor "VETTT CAP"

G protein class: q

Signaling pathway of: Gastrin

IP3 "A TOGA is HH-IP₃ (hippy)"

Signaling pathway of: Vitamin D

steroid (intracellular) receptor "VETTT CAP"

Signaling pathway of: PDGF

Intrinsic tyrosine kinase (TK), MAP kinase pathways "growth factors" - in order to grow, you need insulin, growth factors, and a good MAP

Signaling pathway of: LH

cAMP "FLAT ChAMP" likes to cAMP

Signaling pathway of: hCG

cAMP "FLAT ChAMP" likes to cAMP

Signaling pathway of: IGF-1

Intrinsic tyrosine kinase (TK), MAP kinase pathways "growth factors" - in order to grow, you need insulin, growth factors, and a good MAP

Signaling pathway of: Aldosterone

steroid (intracellular) receptor "VETTT CAP"

Receptors that signal through Gq?

Gq = H1, a1, V1, M1, M3 -\> DAG/IP3 "HAVe 1 M&M"

Signaling pathway of: FSH

cAMP "FLAT ChAMP" likes to cAMP

Signaling pathway of: EGF

Intrinsic tyrosine kinase (TK), MAP kinase pathways "growth factors" - in order to grow, you need insulin, growth **factors**, and a good MAP

Signaling pathway of: ADH (V2)

cAMP "FLAT ChAMP"

what receptors activates the IP3 pathway?

Gq = H1, a1, V1, M1, M3 "HAVe 1 M&M"

β2

G protein class: s

Signaling pathway of: MSH

cAMP "FLAT ChAMP" likes to cAMP

G protein class: q

G protein class: s

Signaling pathway of: oxytocin

IP3 "A TOGA is HH-IP3 (hippy)"

Receptors that signal through Gs?

Receptor Gs (β1, β2, D1, H2, V2) -\> cAMP

Signaling pathway of: calcitonin

cAMP "FLAT ChAMP" likes to cAMP

Signaling pathway of: Prolactin

Receptor-ASSOCIATED tyrosine kinase pathways (ie JAK/STAT) "JAK the PIG does not like camp fires because it can get killed STAT" ^{know that PIG signals thorugh a separate pathway than FLAT}

α1

G protein class: q

Signaling pathway of: GnRH

IP3 "A TOGA is HH-IP3 (hippy)"

Signaling pathway of: TRH

IP3 "A TOGA is HH-IP3 (hippy)"

G protein class: i

Signaling pathway of: IFN

Receptor-ASSOCIATED tyrosine kinase pathways (ie JAK/STAT) "JAK the PIG does not like camp fires because it can get killed STAT" ^{know that PIG signals thorugh a separate pathway than FLAT}

ANP, NO (EDRF) have this signaling molecule in common:

cGMP

Signaling pathway of: Insulin

Intrinsic tyrosine kinase (TK), MAP kinase pathways "growth factors" - in order to grow, you need **insulin**, growth **factors**, and a good **MAP**

Receptors & signaling molecules Flashcards

(59 cards)