Cardiology (3) Flashcards
(47 cards)
Natriuretic peptides induce what
Excretion of Na
H20 follows
Natriuretic peptides are released from what stimulation
Myocytes stretching via increased plasma volume increasing
90% of hypertension is caused by what
Primary
Age related decreased sensitivity of baroreceptors
Secondary hypertension involves what
diseases (renal + endocrine)
Eutrophic remodelling occurs where?
What does this lead to in terms of blood pressure
What does this lead to in terms of SV
Small arteries
increased diastolic pressure
Increased SV
Hypertrophic remodelling occurs where?
What does this lead to in terms of blood pressure
What does this lead to in terms of wall stiffness
Large arteries
Increased systolic pressure
increased wall stiffness
hypertension can cause what disease in the kidney
Hypertensive neuropathy
Hypertensive neuropathy involves what
Renal arteriole thicken due to HTN
Decreased lumen size + BF decreases
Ischaemia of parts of kidney due to low BF
Fibrosis + atrophy
damage to glomerulus
Haemoproteinuria
what happens to blood viscosity in hypertensive patients
Inreased
management of HTN acronym
A C D
ACE inhibitors + angiotensin blockers
Calcium Blockers
Diuretics
ACE inhibitor drug
Ramipril
Angiotensin receptor blocker drug
Caandesartan
Calcium channel blocker (dihydropyridines)
amlodipine
Calcium channel blocker (non-dihydropyridines)
Diltiazem
what do dihydropyridines do?
Vasodilators + Diuretics
What do non-dihydropyridines do?
Negative Ionotropy + chronotropy
Diuretic drug (thiazide)
Indapamide
where do thiazide drugs work on
Distal convulated tubule (DCT)
Diuretic drug (loop on henle)
Furosemide
Diuretic drug (collecting tube)
Spironolactone (aldosterone antagonist)
Moxonide does what
Reduces SNS activity
Doxazosin is what type of blocker
A- Blocker
Baroreceptor reflex affects vaasodilatation through what type of receptors
Alpha receptors
Juxtaglomerular apparatus detect what (2)
Renal perfusion pressure
Sodium concentration
