Resp 3 Flashcards

1
Q

MET meaning

A

Metabolic equivalent of Task

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2
Q

1 MET =

A

3.5 mL/kg/min

240ml/min

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3
Q

At max exercise

Tidal Volume =

A

0.5 x Vital Capacity

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4
Q

Owles Point

A

Critical point of oxygen consumption where ventilation increases more in proportion to oxygen consumption

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5
Q

During ascending, inspired PIO2 is what compared to atmosphere?

A

less

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6
Q

3x acute responses from altitude

A

Hyperventilation

Alkalosis

Diuresis

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7
Q

What happens to 2,3 DPG during acclimatisation

A

Reduces

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8
Q

what mixture of gas is used in diving

A

Helium / Oxygen

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9
Q

Minute Ventilation equation

A

Breathing Frequency x Tidal Volume

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10
Q

What does the respiratory centre consist of (2)

What controls what?

A

Medulla + Pons

Pons regulates the Medulla

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11
Q

Positive Stimulation of the medulla (2)

A

Peripheral Chemoreceptors

Central Chemoreceptors

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12
Q

Peripheral Chemoreceptors stimulated by (3)

A

O2 decreasing

CO2 rising

H+ rising

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13
Q

Central Chemoreceptors stimulated by (2)

A

CO2 increasing

H+ rising

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14
Q

Baroreceptors does what to ventilation

A

Increases BP = decrease Ventilation

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15
Q

J receptors are activated when?

What does it do to ventilation?

A

Activated in Traumas

Increases

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16
Q

What leads to negative stimulation of the medulla/pons? (2)

A

Stretch receptors in lungs

irritant receptors in lungs

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17
Q

Negative stimulation is regulated by what nerve

A

Vagus nerve

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18
Q

Carotid / Aortic Bodies are sensitive to what (3)

A

Low O2

High CO2

High H+

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19
Q

Definition of Oxygen Delivery

A

O2 leaving heart in 1 min

20
Q

Definition of Oxygen Consumption

A

O2 used by body in 1 min

21
Q

Equation of Oxygen Delivery

A

O2 in blood x Cardiac Output

22
Q

Factors affecting oxygen consumption (3)

A

Age

temperature

Exercise

23
Q

Respiratory Exchange ratio

A

Ratio of CO2 production to O2 consumption

24
Q

Affected by respiratory exchange ratio (2)

A

Hyperventilation

Metabolic Fuel

25
Antitussives
Cough Suppressants
26
2 types of suppresants that affects afferent nerves which are cough suppresants
Linctuses Steam
27
Linctuses work where
above larynx
28
antitussives work on what? name 3 types
Medullary cough centre Opiods // Non opiods // sedatives
29
Expectorants increase what?
Volume of secretion
30
Mucolytics decrease what?
Viscosity of secretion
31
Prednisone is what?
Oral Corticosteroid
32
Ciclesonide is what
Glucocorticoid
33
Cromolyn sodium + Nedocromil Sodium
Inhibit MC (eosinophils)
34
Prodrugs are what
Drugs that are biologically inactive unless placed in body
35
Arachidonic acid ---> Leukotriene what enzyme
5 Lipoxygenase
36
Motelukast + Zafirlukast are what
Leukotriene Receptor Antagonists
37
Salbutamol + salmeterol work on what receptors
B2 Adrenoreceptors
38
Theophylline + aminophylline increase what? what drugs are they
increase bronchodilation Methylxanthines
39
Ipratropium + Tiotropium are what type of drug What do they inhibit
Antichilinergic agents Inhibits M3 receptors
40
Omalizumab does what
inhibit IgE to MC
41
Ketotifen does what
histamine receptor antagonist
42
Magnesium sulphate causes what
Bronchodilation
43
ketamine causes what
bronchodilation
44
methylxanthines do what
Directly bronchodilate
45
Sympathomimetics work how
mimic dilator neurotransmitters
46
Antichilinergics do what
block constrictor transmitter