cardiovascular embryology and histology Flashcards

(35 cards)

1
Q

average heart beats per min

A

70

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2
Q

what day does the heart start beating

A

day 22 in utero

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3
Q

what does the heart begin as developmentally

A

a tube of contractile myocardium lined by endothelium (endocardium)

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4
Q

what is the cardiogenic field

A

a horse shoe shaped endothelial tube (primitive heart tube) that develops as blood islands coalesce

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5
Q

where do blood islands form

A

in the visceral layer of the lateral plate mesoderm cranial to the developing brain

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6
Q

what brings the two sides of the cardiac region together

A

lateral body folding

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7
Q

what are the two poles of the heart tube

A

aortic and venous

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8
Q

the caudal pole forms the ___ end of the heart, the cranial pole forms the ____ end of the heart

A

venous

arterial

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9
Q

What happens in cardiac looping

A

the atrial portion (inferior) grows upward and to the left, the ventricular portion (superior) grows downward and to the right

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10
Q

What is the ductus venosus

A

the vein from the placenta that bypasses the embryonic liver and enters the inferior vena cava

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11
Q

what is the ductus arteriosus

A

the vessel that gors from the pulmonary trunk into the aortic arch in the embryonic heart, bypassing the lungs

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12
Q

what is the foramen ovale

A

an opening in the septum secundum through which blood moves from the right atria to the left, bypassing the embryonic pulmonary circut

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13
Q

what are the two things that form the interatrial septum

A

septum primum

septum secundum

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14
Q

when does the interatrial septum form

A

at birth

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15
Q

What are the two causes of ASD

A
  1. excessive resorption of the septum primum

2. absence of the septum secundum

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16
Q

what is the common atrium

A

atria without the septum secundum and primum

17
Q

what is the most common heart defect

A

ventricular septal defects (VSD)

18
Q

what is transpositions of the great vessels

A

the pulmonary trunk and aorta are attached to the wrong ventricles, leading to two separate circuits. respiratory and systemic

19
Q

what are the four things that happen in the tetralogy of fallot

A
  1. ventricular septal defect
  2. pulmonary trunk sepsis
  3. overriding aorta
  4. right ventricle hypertrophy
20
Q

what is persistent truncus arteriosus

A

when the conotruncal septum doesn’t form and the aorta and pulmonary trunk are combined

21
Q

what are the parts of the conducting system of the heart in order

A
SA node (pacemaker)
AV node
AV bundle
bundle branches
perkinje fibers
22
Q

how are electrical stimuli propegated through the heart

23
Q

What are the three layers of the heart wall from external in internal

A

epicardium
myocardium
endocardium

24
Q

what are the characteristics of the epicardium

A

same thing as the visceral layer of the pericardium

simple squamous epithelium

25
what are the characteristics of the myocardium
``` muscle cells (cardiac myocytes) makes up the majority of the heart wall ```
26
what are the characteristics of the endocardium
inner lining of the heart chambers simple squamous epithelium near perkinje fibers continuous with great vessels
27
What are the layers of the vessels
tunica adventitia tunica media tunica intima
28
What are the characteristics of elastic arteries
thick tunica adventitia, broad media with elastin
29
what are the characteristics of muscular arteries
thick tunica media, IEL, EEL
30
what are the characteristics of capillaries
very thin endothelial membrane precapillary sphincters site of gas and nutrient exchange
31
What are the three types of capillaries
continuous fenestrated discontinuous (sinusoidal)
32
where are continuous capillaries found
most tissues
33
where are fenestrated capillaries found (increased permeability)
small intestines kidney glomerulus endocrine glands
34
Where are discontinuous capillaries found (high permeability)
liver, spleen, endocrine glands, hematopoetic
35
how do veins compare to arteries
lower pressure, thinner walls, closer to the skin and have valves (muscle pumps)