Cardiovascular system drugs Flashcards
(30 cards)
chronotropic drugs
affect heart rate
positive chronotropic drugs
increase heart rate
negative chronotropic drug
decrease heart rate
inotropic drugs
affect strength of heart contractions
positive inotropic drugs
increase strength of contractions
negative inotropic drugs
decrease strength of contractions
compensatory mechanisms of heart to raise bp
increase HR, increase stroke volume, increase efficiency of contraction, cardiac remodeling
diseases of the heart
valvular disease, cardiac arrhythmias, mycocardial disease, congenital problems
treatment principals of cardiac disease
control rhythm disturbances, maintain/increase cardiac output, relieve fluid accumulations, increase oxygenation of blood, sedatives/oxygen
glycosides
digoxin
diuretics
furosemide, hydrochlorothiazide, chlorothiazide, spironolactone
catecholamines
epinephrine, dopamine, dobutamine, isoproterenol
bipyridine derivatives
amrinone, milrinone
factors that predispose heart to arrhythmias
conditions that cause hypoxia, electrolyte imbalances, sensitivity to catecholamines, certain drugs (digoxin), cardiac trauma
antiarrhythmic drug classes
1A, 1B, 1C, II, III, IV
1A antiarrhythmic drugs
quinidine, procainamide
1B antiarrhythmic drugs
lidocaine, tocainide, mexiletine
1C antiarrhythmic drugs
flecainide, encainide (not used)
II antiarrhythmic drugs
beta-adrenergic blockers; propranolol, atenolol
III antiarrhythmic drugs
bretylium, aniodarone, sotalol
IV antiarrhythmic drugs
calcium channel blockers; verapamil, diltiazem
arteriolar dilators
hydralazine
venodilators
nitroglycerine
combined vasodilators
prazosin, nitroprusside