Cartilage and Bone Flashcards

1
Q

where is cartilage found

A

protecting the ends of long bones and joints, between vertebrae, ends of ribs etc

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2
Q

what is the function of cartilage

A

provides support and resistance to compression

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3
Q

what are the three types of cartilage

A

hyaline cartilage - most common, found in nose, ribs etc
fibro cartilage - fibrous, lots of collagen. found in intervertebral disc
elastic cartilage - flexible e.g epiglottis

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4
Q

what are the two different bone conformations

A

compact (cortical)

spongy (trabecular)

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5
Q

What makes up the unmineralised organic component of bone ECM

A

osteoid

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6
Q

what makes up the mineralised component of bone ECM

A

hydroxyapatite

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7
Q

osteogenic cell

A

bone cell precursor that gives rise to osteoblasts

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8
Q

osteons

A

circular units made of of layers of bone tissue

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9
Q

central canals

A

canals in the centre of osteons that contain vessels and nerves

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10
Q

concentric lamellae

A

layers of bone tissue making up osteons

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11
Q

perforating canals (volkmanns canals)

A

run perpendicular to and allow connections between central canals

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12
Q

interstitial lamellae

A

layers of bone tissue in between osteons (concentric lamellae)

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13
Q

circumferential lamellae

A

layers of bone tissue surrounding entire bone

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14
Q

lacunae

A

small osteocyte containing spaces in-between lamellae

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15
Q

canaliculli

A

tiny canals connecting lacunae

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16
Q

what is spongy bone composed of

A

criss crossing branches called trabeculae

17
Q

what is found in the spaces between trabeculae

A

red and yellow bone marrow

18
Q

endosteum

A

thin membrane lining external surface of spongy bone

19
Q

periosteum

A

layer surrounding bone tissue except at joints

20
Q

osteomalacia

A

osteoid not adequately mineralised due to dietary deficiencies e.g. lack of calcium
bones are weak and prone to fracture, delayed tooth eruption and enamel hypoplasia

21
Q

osteoarthritis

A

excess bone tissue as it tries to replace lost cartilage

22
Q

rheumatoid arthritis

A

bona and cartilage both lost

23
Q

periodontitis

A

increased osteoclastogenesis of alveolar bone

can cause tooth loss