Case 1- vocab Flashcards
(16 cards)
What is acanthosis
Diffuse epidermal hyperplasia . Increased thickening of the stratum basale and stratum spinosum
What is acantholysis?
disruption of the intercellular connections between keratinocytes of the epidermis, caused by lysis of intercellular cement substance. It is associated with the formation of epidermal vesicles in such conditions as pemphigus vulgaris, pemphigus foliaceus, and other skin disorders.
What is auspitz sign
Bleeding that occurs after psoriasis scales have been removed. I occurs because the capillaries run close to the skin surface under a psoriasis lesion. It can be in other scales disorders as well.
What is a bulla
Large blisters on the skin that are filled with clear fluid
What is hyperkeratosis
Thickening of the stratum corneum, often associated with a quantitative abnormality of the keratin and is usually associated with the granular layer . Can be caused by a vit a deficiency
What is Koehler phenomenon
also called the “Koebner response” or the “isomorphic response”, refers to skin lesions appearing on lines of trauma.
- in psoriasis plaques will form at site of skin injury
What is lentigo
lentigo is a small, sharply circumscribed, pigmented macule surrounded by normal-appearing skin. Histologic findings may include hyperplasia of the epidermis and increased pigmentation of the basal layer.
What is a munro microabscess
A microscopic collection of polymorphonuclear white blood cells found in the stratum corneum in psoriasis. Also called Munro’s abscess.
What is Pautrier microabscess
A microscopic lesion in the epidermis, seen in mycosis fungoides; it is composed of the same type of atypical mononuclear cells as those that form the infiltrate in the corium.
What is a psoriasiform
a dermatosis resembling psoriasis
What is a vesicle
a liquid-filled cavity under the epidermis, commonly called a blister
What is a Heberden node
are hard or bony swellings that can develop in the distal interphalangeal joints (DIP) (the joints closest to the end of the fingers and toes). They are a sign of osteoarthritis and are caused by formation of osteophytes (calcific spurs) of the articular (joint) cartilage in response to repeated trauma at the joint.
What is pannus
- Inflamed hyperemic synovium, causes erosion of underlying cartilage-mediators cause osteoclastic activity-form juxta-articular erosions, subchondral cysts, osteoporosis
- Pannus can bridge bones and eventually become fibrous and then bony forming an ankylosis
- May also see inflammation of tendons and ligaments- inflame synovial sheath and can extend into muscle
What is Synarthrosis
a bony junction that is immovable and is connected by solid connective tissue, comprising the fibrous joints and the cartilaginous joints.
What is Synovium
a thin membrane in synovial (freely moving) joints that lines the joint capsule and secretes synovial fluid
What is an Osteophyte
commonly referred to as bone spurs or parrot beak,[1] are bony projections that form along joint margins
