CC DAY-2

Question 1

Process by which lab ensures quality results by closely monitoring pre-analytical, analytical and post-anal. stages of testing

Answer 1

Quality assessment/assurance

Question 2

Everything that precedes test performance

Answer 2

Pre-analytical

Question 3

everything that related to assay

Answer 3

analytical

Question 4

everthing that comes after test analysis

Answer 4

post-analytical

Question 5

all the labs policies, processes, procedures, and resources needed to achieve quality testing

Answer 5

quality system

Question 6

announced that a periodic performance review (PPR) will be required for the laboratory accreditation program

Answer 6

The Joint Commission

Question 7

part of analytical phase of quality assurance

Answer 7

quality control

Question 8

system ensuring daily accuracy and precision in the lab by including quality control reagents in every series of measurements

Answer 8

intralab/interlab QC

Question 9

long term accuracy of results from lab by comparing lab results from other labs

Answer 9

interlab QC

Question 10

process of testing and adjusting analyzers readout to establish correlation between measured and actual concentrations.

Answer 10

calibration

Question 11

formerly called standard.
this is a reference material with known concentration of analyte

Answer 11

calibrator

Question 12

when will CALIBRATION VERIFICATION required?

Answer 12

every 6 months when lot no of reagents changes, following preventive maintenance or repair, and when controls are out of change.

Question 13

measures of dispersion (3)

Answer 13

standard deviation
coefficient of variation
range

Question 14

difference between highest and lowest values in data set

Answer 14

range

Question 15

sum of all observations
average of all observations

Answer 15

mean

Question 16

statistical expression of dispersion of values around mean. requires min. 20 values

Answer 16

standard deviation

Question 17

expresses standard deviation as percentage

Answer 17

coefficient of variation

Question 18

QC CONTROL CHART

a population probability distribution that is symmetric about the mean

a.CUSUM
b. Gaussian Curve
c. Youden/Twin Plot
d. Shewart levey-jennings charts

Answer 18

Gaussian Curve

Question 19

QC CONTROL CHART

calculates difference between QC results and the target means.

a.CUSUM
b. Gaussian Curve
c. Youden/Twin Plot
d. Shewart levey-jennings charts

Answer 19

CUSUM- Cumulative sum graph

Question 20

QC CONTROL CHART

earliest indication of systematic error specifically SHIFTS

a.CUSUM
b. Gaussian Curve
c. Youden/Twin Plot
d. Shewart levey-jennings charts

Answer 20

CUSUM- Cumulative sum graph

Question 21

QC CONTROL CHART

used to compare results obtained on a high and low control serum from different labs

a.CUSUM
b. Gaussian Curve
c. Youden/Twin Plot
d. Shewart levey-jennings charts

Answer 21

c. Youden/Twin Plot

Question 22

QC CONTROL CHART

most widely used
easily identifies random and systematic errors

a.CUSUM
b. Gaussian Curve
c. Youden/Twin Plot
d. Shewart levey-jennings charts

Answer 22

d. Shewart levey-jennings charts

Question 23

6 consecutive control values on same side of the mean

Answer 23

shift

Question 24

main cause of SHIFT

Answer 24

improper calibration

Question 25

control values increasing or decreasing for 6 consecutive runs

Answer 25

trend

Question 26

main cause of TREND

Answer 26

deterioration of reagents

Question 27

Random error AKA

Answer 27

indeterminate, unpredictable, Imprecision

Question 28

error that doesnt recur in regular pattern due to environmental or operator conditions a. random error b. systematic error

Answer 28

a

Question 29

electro-optical mechanism a. random error b. systematic error

Answer 29

a

Question 30

13s and r4s westgard rule a. random error b. systematic error

Answer 30

a

Question 31

Systematic error AKA

Answer 31

determinate, predictable, inaccuracy

Question 32

recurring error inherent in test procedure, observations consistently in one direction a. random error b. systematic error

Answer 32

b

Question 33

optical changes a. random error b. systematic error

Answer 33

b

Question 34

how close measurement is to the true value

Answer 34

accuracy

Question 35

reproducibility

Answer 35

precision

Question 36

how close results are when same sample is tested multiple times

Answer 36

precision

Question 37

formerly called normal value

Answer 37

reference interval

Question 38

reference interval is established by testing minimum of _____________ subjects

Answer 38

120 healthy indiv.

Question 39

lowest concentration of substances that can be detected by test method a. analytical sensitivity b. analytical specificity

Answer 39

a

Question 40

Desirable in screening tests a. analytical sensitivity b. analytical specificity

Answer 40

a

Question 41

ability of method to measure only the analyte its supposed to measure and not other related substances a. analytical sensitivity b. analytical specificity

Answer 41

b

Question 42

desirable in confirmatory tests a. analytical sensitivity b. analytical specificity

Answer 42

b

Question 43

% of population WITH the disease that test POSITIVE a. diagnostic sensitivity b. diagnostic specifity c. PPV d. NPV

Answer 43

a

Question 44

% of population WITHOUT the disease that test NEGATIVE a. diagnostic sensitivity b. diagnostic specifity c. PPV d. NPV

Answer 44

b

Question 45

% of time that a positive result is correct a. diagnostic sensitivity b. diagnostic specifity c. PPV d. NPV

Answer 45

c

Question 46

% of time that a negative result is correct a. diagnostic sensitivity b. diagnostic specifity c. PPV d. NPV

Answer 46

d

Question 47

monitoring and diagnosis of disease/ measures of diagnostic efficiency (4)

Answer 47

diagnostic sensitivity diagnostic specifity PPV NPV

Question 48

in correlation study, it requires a minimum of _______ samples

Answer 48

40 patient samples

Question 49

critical values include what tests? (9)

Answer 49

glucose sodium potassium magnesium calcium phosphorus total CO2 blood gases total biliribun (in neonates)

Question 50

testing of unknowns submitted by outside agency. results reported to agency, which compares them to results from other labs

Answer 50

Proficiency testing