Cell birth and death

Question 1

loss of proliferation controls only

Answer 1

Benign

Question 2

loss of both proliferation and positional controls

Answer 2

malignant

Question 3

proliferation continues even in the absence of an external stimulus

Answer 3

neoplasia

Question 4

altered proliferative states of cells that are reversible: proliferation and tissue damage stops when the stimulus that provoked it is removed

Answer 4

regeneration
hyperplasia
metaplasia
dysplasia

Question 5

neoplasia

Answer 5

irreversible proliferation of cells

Question 6

two major forms of neoplasia

Answer 6

benign

malignant

Question 7

least perturbed state

Answer 7

regeneration

Question 8

following balloon angioplasty what happens?

Answer 8

endothelial cell injury

Question 9

endothelial cells regenerate after a balloon angioplasty

Answer 9

to re-from the lumenal lining

Question 10

increase in the number of cells in the tissue but the cells are fully functional

Answer 10

Hyperplasia

Question 11

Grave’s disease

Answer 11

hyperthyroidism

Question 12

hyperthyroidism is an example of

Answer 12

hyperplesia

Question 13

_______ _____ in Bone Marrow following Blood loss

Answer 13

Erythrocyte hyperplasia

Question 14

replacement of one cell type with another cell type

Answer 14

metaplasia

Question 15

_____ of __________ _____ cells during chronic pelvic inflammatory disease

Answer 15

metaplasia of endocervical epithelial cells

Question 16

frequent pre-courser to cancer

Answer 16

Dysplasia

Question 17

factoid of dysplasia

Answer 17

it can be stopped but not very reversible to original cell state

Question 18

loss of orientation in the tissue, pleotropic cells (vary of sizes and nucleic)

Answer 18

dysplasia

Question 19

large nuclei is indicative of ?

Answer 19

high metabolic activity

Question 20

examples of dyplasia

Answer 20

pap smear and moles

Question 21

example of a benign neoplasia

Answer 21

uterine fibroid

Question 22

what are the symptoms of fibroids?

Answer 22

abnormal and heavy bleeding; pain and pressure; fertility problems

Question 23

malignant neoplasia

Answer 23

cancer

Question 24

example of a positional control of proliferation

Answer 24

lumen of the Gut

Question 25

slowly dividing cell

Answer 25

stem cells

Question 26

positional control decided by the

Answer 26

extracellular matrix

Question 27

R point factoid

Answer 27

defective in most cancers

Question 28

phases of mitosis (8)

Answer 28

``` interphase early prophase metaphase early anaphase late prophase prometaphase late anaphase late telophase ```

Question 29

basic cell cycle

Answer 29

G1 phase synthesis G2 phase M phase (mitosis/cytokinesis)