Cell Birth And Death I- Lecture 9/9/21

Question 1

Reversible proliferation states (4)

Answer 1

Regeneration, hyperplasia, meta plasma, dysplasia

Question 2

Neoplasia

Answer 2

Synonymous with tumor, proliferation continues even in the absence of an external stimulus

Question 3

Benign

Answer 3

Loss of proliferative controls only

Question 4

Malignant

Answer 4

Loss of both proliferative and positional controls (cancer)

Question 5

Regeneration

Answer 5

One to one replacement of a cell, could follow injury, cells are differentiated and identical except to parent

Question 6

Hyperplasia

Answer 6

Increases in the number of cells, all cells differentiated

Question 7

Examples of pathogenic hyperplasia (2)

Answer 7

Smooth muscle hyperplasia following angioplasty, Graves’ disease (hyperthyroidism)

Question 8

Physiologic example of hyperplasia

Answer 8

Erythrocyte hyperplasia caused by elevated altitudes or blood loss

Question 9

Metaplasia

Answer 9

When cells are replaced with different cell types to protect other tissues, sacrifices other functionality

Question 10

Example of metaplasia

Answer 10

Chronic pelvic inflammatory disease, ciliated epithelial cells of the endocervix replaced by squamous layer

Question 11

Dysplasia

Answer 11

Acquired mutation “on the way” to cancer cells, big nucleus different cell size, mitotic features

Question 12

Examples of dysplasias

Answer 12

Dysplasia of the Exocervix, Moles

Question 13

Endocervix

Answer 13

Uterine side of the cervix, lines with ciliated epithelial cells for fluid, sperm moving

Question 14

Exocervix

Answer 14

Vaginal side, squamous epithelium