Development I-Lecture 9/20/21 Flashcards

1
Q

Embryonic period

A

First 8 weeks of gestation

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2
Q

Fetal period

A

The remainder of the gestation period after 8 weeks

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3
Q

Gametes

A

Specialized germ cells from the male and the female, haploid in chromosome number

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4
Q

End of female gametogenesis

A

Fertilization

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5
Q

Meiosis

A

To consecutive cell divisions with one round of DNA replication, leading to haploid cells

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6
Q

Relative size of male and female gametes

A

Ovum can be 100s of times bigger

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7
Q

Acrosome

A

Modified Golgi body that contains enzymes necessary to penetrate zona pellucida

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8
Q

Mid-piece of tail

A

Contains all mitochondria necessary for energy production in the flagella

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9
Q

When are sperm produced

A

Puberty onward in males

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10
Q

HPO axis

A

Hypothalamus to pituatary to ovary axis

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11
Q

Hormone production by hypothalamus

A

GnRH, stimulates pituitary

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12
Q

Hormone production by pituitary

A

FSH and LH, stimulates the ovaries

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13
Q

Hormone production by the ovaries

A

Estrogen and progesterone, stimulates the uterus

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14
Q

GnRH mechanism of action

A

Stimulates the synthesis and secretion of FSH and LH

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15
Q

FSH mechanism of action

A

Stimulates ovarian follicle growth, differentiation and steroidogenesis

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16
Q

LH mechanism of action

A

Stimulates ovulation, corpus outrun formation and steroidogenesis

17
Q

Progestins source

A

Corpus luteum

18
Q

LH surge

A

A sharp increase in LH plasma levels that stimulates ovulation caused by increase in estrogen levels

19
Q

Primary follicle

A

Oocyte is arrested in prophase of meiosis I

20
Q

Secondary follicul

A

Stimulated by LH surge, arrested in metaphase of meiosis II

21
Q

Graafian follicle

A

The mature follicle that gets ovulated

22
Q

Ovulation

A

PGE2 stimulates muscle contraction of the thecal cells surrounding follicle, expelling the oocyte towards the Fallopian tube

23
Q

Zona palucida

A

Proteinacious zone surrounding oocytes

24
Q

Cumulus oophorus

A

Cells that attach the oocytes to the follicular cells

25
Antrum
Follicular portion that is filled with nutrient rich fluids
26
Follicular secretion
FSH stimulated 8-12 follicles to grow every month and secrete estrogen
27
What determines the dominant follicle
Fastest growing follicle, has the most FSH receptors
28
Degeneration of losing follicles
Degenerate via apoptosis
29
Theca cells
The smooth muscle like cells that is triggered by PGE2
30
Corona Radiata
The few layers of follicular cells that go with the egg after ovulation
31
Down syndrome
Trisomy 21 caused by the non-disjunction
32
Fertilization
Occurs in the ampulla of the Fallopian tube, cannot occur in the uterus