Cell compartimentalization Flashcards
Protein sorting and vesicular traffic (15 cards)
What is the primary function of protein sorting in cells?
To direct proteins to their correct cellular locations for proper function.
True or False: Vesicular traffic involves the movement of proteins within the endomembrane system.
True
Fill in the blank: The process by which proteins are transported into the nucleus is called __________.
nuclear import
Name two main types of protein sorting mechanisms
Signal-based sorting and vesicular transport.
Which organelle is primarily involved in the sorting and dispatching of proteins?
The Golgi apparatus.
Multiple Choice: Which of the following is NOT a step in vesicular traffic? A) Budding, B) Fusion, C) Translation, D) Targeting
C) Translation
What role do signal peptides play in protein sorting?
They direct the nascent proteins to their correct destinations.
True or False: Nuclear export requires nuclear localization signals.
False
What is the main mechanism by which proteins exit the nucleus?
Receptors (exportins) coupled with active small G proteins (Ran) bind a specific protein, to be transported through the nuclear pore
Fill in the blank: Proteins destined for the ______ contain an signal sequence.
Endoplasmic reticulum
What is the difference between constitutive and regulated secretion?
Constitutive secretion occurs continuously, while regulated secretion occurs in response to specific signals.
Multiple Choice: Which of the following is involved in vesicle budding? A) Clathrin, B) Myosin, C) Actin, D) Tubulin
A) Clathrin
What is the role of SNARE proteins in vesicular traffic?
They mediate the fusion of vesicles with their target membranes.
True or False: Proteins can only be sorted and transported in vesicles.
False
What is the significance of the nuclear localization signal (NLS)?
It allows proteins to be recognized and transported into the nucleus.
