Endoplasmic reticulum

Question 1

What is the primary role of the signal recognition particle (SRP)?

Answer 1

To recognize and target specific proteins for translocation into the endoplasmic reticulum.

Question 2

Fill in the blank: The SRP binds to the ribosome and the _____ during protein synthesis.

Answer 2

signal peptide

Question 3

Multiple Choice: Which of the following is NOT a role of the signal recognition particle? a) Targeting proteins b) Protein folding c) Stopping protein synthesis d) Guiding ribosomes

Answer 3

b) Protein folding

Question 4

True or False: Protein folding occurs only in the Golgi apparatus.

Answer 4

False

Question 5

What are the two main types of traffic to/from the Golgi?

Answer 5

Anterograde transport (from the ER to Golgi) and retrograde transport (from Golgi back to ER).

Question 6

Multiple Choice: Which organelle is primarily responsible for protein folding? a) Nucleus b) Golgi apparatus c) Endoplasmic reticulum d) Lysosome

Answer 6

c) Endoplasmic reticulum

Question 7

True or False: Protein folding can be a spontaneous process that requires no energy.

Answer 7

True

Question 8

What role does the SRP play in the translocation of proteins?

Answer 8

It helps direct the ribosome to the endoplasmic reticulum membrane.

Question 9

What is the role of chaperone proteins in protein folding?

Answer 9

They assist in the proper folding of polypeptides into functional proteins.

Question 10

A cotranslational modification of peptides occurring in ER is_________________

Answer 10

N-glycosilation