Cell Components/Structure Flashcards

1
Q

Plasma membrane

A

Separates the internal structures of the cell from the outside environment but allows for selective permeability

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2
Q

What is a plasma membrane made of

A

Phospholipid bilayer
Phosphate head = hydrophilic
Lipid tail = hydrophobic

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3
Q

Selective permeability

A

Selects what can get through from one side to another

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4
Q

What can permeable across a plasma membrane?

A

Non polar
Uncharged
e.g o2 co2 and steroids

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5
Q

What impermeable across a plasma membrane?

A

Ions and large uncharged molecules

e.g Glucose

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6
Q

What is slightly permeable across a plasma membrane?

A

Small polar molecules

e.g water

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7
Q

What other proteins and lipids are in the plasma membrane?

A

Cholesterol
Glycocalyx
Peripheral proteins
Integral membrane proteins

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8
Q

Role of cholesterol

A

helps shaping membrane

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9
Q

Role of glycocalyx (glycoproteins and glycolipids)

A

Functions in cell communication, immune system and cell adhesion

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10
Q

Role of peripheral proteins

A

Not securely attached to lipid bilayer, form relatively loose attachments with the polar heads or integral proteins

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11
Q

Role of integral membrane proteins

A

Securely embedded within or through the lipid bilayer (transmembrane proteins)
Transport proteins including ions and large uncharged particles that can not pass bilayer
Most proteins only bind with a specific molecule like the lock and key theory

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12
Q

Cytoplasm

A

Consists of structure inside the cell (organelles) and the surrounding fluid

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13
Q

Nucleus

A

A large structure inside the cell (organelle) that contains most of the cells genetic material (DNA)

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14
Q

Organelles in a cell

A
Ribosomes
Endoplasmic reticulum (rough and smooth)
Golgi Apparatus
Lysomes
Mitochondria
Cytoskeleton
Centrosome
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15
Q

Cytosol

A

Intracellular fluid that is 70-90% water and contains other components such as ions, ATP, proteins and waste products

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16
Q

Organelles

A

Specialised structures that perform specific functions within the cell

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17
Q

Ribosomes

A

Where proteins are manufactured
Composed of a large and small subunit
Found on rough ER, free floating in cytosol and in mitochondria

18
Q

Endoplasmic recticulum

A

A network of membrane forming flattened sacs

Manufacturing and packing system

19
Q

Rough ER

A

A network of membranes that is continuous with nuclear membrane and has ribosomes attached
Proteins made by attached ribosomes enter the sacs of the rough ER for further processing and sorting

20
Q

Smooth ER

A

Extends from the rough ER but does not contain ribosomes.

It synthesises fatty acids and steroids and in the liver it helps to detoxify harmful substances

21
Q

Golgi Apparatus

A

Composed of flattened membrane sacs (Cisternae)
It modifies, sorts, packages and transports proteins received by the rough ER
Processed proteins leave the cisternae in a vesicle

22
Q

Lysomes

A

Vesicles of membrane pinched off from the golgi complex

They contain an array of enzymes capable of breaking down a wide variety of molecules not wanted or needed by the cell

23
Q

Mitochondria

A

Performs the chemical reactions that use oxygen to produce ATP
Inner membrane is highly folded into structures called cristae which increases the surface area for chemical reactions to take place
Contaisn DNA molecule

24
Q

Cytoskeleton

A

The cells internal supporting framework

Made up of tiny, flexible fibres and rigid, rod like pieces

25
Types of Cytoskeleton and their role
Intermediate filaments - Provide support and shape | Microtubules and microfilaments - Involved in the movement of cells or cell components
26
Centreosome
Composed of microtubules | Plays a role during cellular division, pulling chromosomes apart before cells split
27
Enzymes
Proteins which function to help metabolic reactions to occur Chemical catalysts Reduce the activation energy needed for a reaction
28
Effect of pH and temperature on Enzymes
At suboptimal temperature or pH it changes the shape of the active side on an enzyme so its substrate can no longer fit
29
Nuclear envelope
A double membrane that surrounds the nucleus separating the contents of the nucleus from the rest of the cytoplasm
30
DNA molecule
Stored as double stranded in the form of an double helix
31
DNA form when cell is ready to copy itself
Packed in chromosomes
32
DNA form when the cell is ready to make proteins
Unpacked so genes can be read
33
Stages of DNA formation
``` DNA double helix Nucleosome Chromatin Chromatin fibre Loop Chromatid Chromosome ```
34
Nucleosome
DNA wrapped around histones
35
Chromatin
Nucleosomes linked together
36
Chromatin fibre
Lots of chromatin
37
Chromatid
Chromatin fibre forming a loop shape which forms a chromatid
38
Chromosome
Two chromatids join with a centromere in the middle
39
Protein synthesis stages
Transcription | Translation
40
Transcription process and where it occurs
Make mRNA from DNA Occurs in nucleus DNA double helix is opened and the sequence of gene is converted (transcribed) into a sequence of mRNA Transcribed mRNA exits nucleus through nuclear pores, entering cytosol and binding to a ribosome
41
Pairing sequence from DNA to mRNA
A/U, T/A, G/C, C/G
42
Translation
Protein formed for mRNA Occurs in cytoplasm (at ribosome) mRNA sequence is read and translated into an amino acid sequence by a ribosome Three mRNA nucleotides = one amino acid Translation of mRNA ends when a "Stop" mRNA sequence is reached At that point the protein detaches from the ribosome