Cellular Membrane Flashcards
- Structure & function - Classes of membrane proteins - Membrane transport processes (23 cards)
What is the main function of phospholipids?
To selectively isolate the cell’s (or organelle’s) internal content from the external environment.
What are the main functions of proteins?
- Regulates the flow of material into and out of the cell.
- Allows for interaction with other cells and the extracellular environment.
- Regulate some biochemical reactions.
- Help cells attach together.
What are the four main classes of membrane proteins and their functions?
- Adhesion proteins: attach the cell to other cells or non-living protein surfaces.
- Enzymes: catalyze chemical reactions that occur at a cell membrane.
- Transport proteins: move substances across the membrane that would not normally be able to cross on their own.
- Receptor proteins: involved in cell-cell communication, recognize and bond to specific molecules in the extracellular environment.
What is the function of enzymes?
To catalyze chemical reactions that occur at a cell membrane.
What is the function of adhesion proteins?
To attach the cell to other cells or non-living protein surfaces.
What is the function of transport proteins?
To move substances across the membrane that would not normally be able to cross on their own.
What are the two kinds of transport proteins?
- Carrier proteins.
- Channel proteins.
What are the four major components of cellular membrane?
- Two layers of phospholipids (lipid bilayer).
- Proteins.
- Carbohydrates.
- Cholesterol (a steroid lipid).
What is the function of receptor proteins?
Involved in cell-cell communication, recognize and bond to specific molecules found in the extracellular environment, and relay messages to relevant locations in the cytoplasm.
What are the characteristics of the (potentially) diffusing molecule to consider?
- Polarity (polar or non-polar).
- Size (small or large).
The membrane is said to be __________ in order to make diffusion across membranes possible.
Selectively permeable.
What characteristics can make diffusion across membranes easier?
- Hydrophobic (non-polar).
- Small.
What are the aspects of passive transport?
- The molecule crosses the membrane without the use of energy.
- May be transported using a molecule or may diffuse across on its own.
- The molecule is moving DOWN its concentration gradient.
What is used in active transport?
Energy (often from ATP).
Active transport is used for transport when…
- Going up the concentration gradient.
- Many molecules are transported at the same time.
- The object is relatively large.
For active transport, does the rate of transport depend on concentration gradient magnitude?
No.
What are the 3 types of passive transport? What are their characteristics?
- Simple diffusion: The molecule diffuses on its own through the lipid bilayer.
- Facilitated diffusion: The molecule uses a channel or carrier to cross.
- Osmosis: Movement of water across the membrane.
For passive transport, how does facilitated diffusion work?
- Binding of cargo molecules to binding site on carrier protein.
- Carrier proteins change shape.
- Release of large molecules on the other side of the membrane.
- Carrier returns to its original shape.
What are the three types of active transport?
- Channel or carrier protein pumps.
- Endocytosis.
- Exocytosis.
How do protein pumps work?
- Binding of cargo molecules to binding site on carrier protein, ATP also bonds to its own binding site.
- A phosphate group is broken off ATP, providing the energy required for the carrier to change shape.
- The cargo molecule is released on the other side of the membrane and ADP + phosphate are released from the ATP binding site.
- Carrier returns to its original shape.
How does endocytosis work?
Large objects or many molecules are taken into the cell (membrane) at the same time by being enclosed in a vesicle.
How does exocytosis work?
A cell transports substances (like proteins or waste) out of the cell by packaging them in a vesicle, which then fuses with the cell membrane and releases the contents outside.
What are exergonic biochemical reactions?
They release energy because the products have less energy than the reactants. These reactions are spontaneous.