Metabolism Flashcards
- Energy carriers - Glycolysis overview - Cell respiration overview - Oxydation of pyruvate to acetyl CoA - Citric acid cycle (Krebs cycle) - Oxidative phosphorylation (9 cards)
What is the overall equation of the breakdown of 1 glucose molecule?
C6H12O6 + 6 O2(g) + 32 ATP + 36-38 PO4 -> 6 CO2(g) + 6 H2O(g) + 32 ATP
What are the 4 pathways of glucose metabolism? What do they require? And where do they happen?
- Glycolysis: does not require O2(g), cytosol
(called anaerobic cellular respiration)
all require high [O2(g)], and happen in the mitochondria,aerobic - Oxidation of pyruvate: mitochondrial matrix
- Citric acid cycle: mitochondrial matrix
- Oxidative phosphorylation: inner mitochondrial membrane
Overview of glucose breakdown
in the cytosol: Glucose -> 2 pyruvate,
In the mitochondrial matrix: 2 pyruvate -> 2 acetyl-coenzymeA -> 4 CO2
What is the location, purpose and products/reactants of glycolysis?
Location: Cytosol
Purpose: initiate glucose breakdown
Reactants: C6H12O6 + 2 ADP + 2 PO4 + 2 NAD+
Products: 2 pyruvate + 2 ATP + 2 NADH
What happens after glycolysis if there’s no O2 ? What about if there’s a sufficient quantity?
Fermentation
If [O2(g)] sufficient : aerobic cellular respiration
What is the location, purpose and products/reactants of oxidation of pyruvate?
Location: mitochondrial matrix
Purpose: to put carbons from pyruvate into a form
that can enter the citric acid cycle
Reactants: 2 pyruvate + 2 coenzyme A + 2 NAD+
Products: 2 acetyl-coenzymeA + 2 NADH + 2 CO2
What is the location, purpose and products/reactants of oxidative phosphorylation?
Location: inner mitochondrial membrane
Purpose: to generate the majority of the cell’s ATP
Reactants: all the high energy electrons of the previous steps +O2(g)
Products: 32 ATP
What is the location, purpose and products/reactants of the citric acid cycle?
Location: mitochondrial matrix
Purpose: generate many high-energy electrons
Reactants: 2 acetyl-coenzymeA
Products: 6 NADH + 2 FADH2 + 4 CO2(g) +2 ATP
What is glucose metabolism
Glucose metabolism refers to the biochemical processes that break down glucose (C₆H₁₂O₆) to produce energy (ATP) and building blocks for cellular functions.
