Central Dogma Flashcards

1
Q

Genes reside at particular locations on a particular chromosome

A

Morgan, Sturtevant

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2
Q

They formulated the one gene-one enzyme hypothesis

A

Beadle and Tatum

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3
Q

What transcribes rRNA (larger RNA), mRNA (small nuclear RNA), tRNA

A

RNA pol I
RNA pol II
RNA pol III

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4
Q

Trims primary transcripts

A

RNA processing

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5
Q

RNA polymerase I is assisted by __ to form the ___

A

GTFs general transcription factors
PIC preinitiation complex

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6
Q

Missing from mature mRNAa, Eukaryotic cells contain this

A

Intervening sequence

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7
Q

The presence of genes with an intervening sequences are called __

A

Split genes

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8
Q

siRNA and miRNA are able to pass through here, and is able to connect plant cells to one another

A

Plasmodesmata

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9
Q

All mature tRNAs have triplet sequence __ ate their 3 prime end

A

CCA

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10
Q

Eukaryotic cells require at least __ initiation factors comprising a total of more than __ polypeptide chains

A

12
25

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11
Q

Binding of the second aminoacyl-tRNA to A site requires __, elongation factor EF-Tu

A

GTPase
responsible for binding aminoacyl tRNA (aa-tRNA) to the ribosome

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12
Q

increases the rate of protein synthesis

A

polyribosome

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13
Q

4 steps of elongation

A

Aminoacyl trna selection
Peptide bond formation
Translocation
Releasing the deacylated tRNA

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14
Q

Responsible for 30 % of inherited disorders

A

Nonsense mutation

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15
Q
A
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