Nature of gene and genome Flashcards
First to use drosophila (fruit flies) for genetic research
Thomas hunt morgan
Linkage into nucleic acid polymers
5 ___ and 3 __ group
Phosphate
Sugar hydroxyl group
__ rule of DNA base composition whein A= T and G=C
Chargaff`
__ is the exterior of DNA molecule, and the __ and interior
sugar phosphate backbone
Bases
3 primary function of DNA
Storage of genetic infor
Replication and inheritance capability
Expression of genetic message
changes the level of DNA supercoiling
Topoisomerases
Type 1- transient break in one strand
Type 2- transient break in both strand
Highly repeated DNA sequences
Satellite DNA- short sequences, evolve rapid
Minisatellite DNA- unstable
Microsatellite DNA-shortest sequences, implicate disorders
How are noncoding elements scattered in the genome?
grouped into SINEs and LINEs (short-long interspersed elements)
resembles globin genes but are nonfunctional
pseudogenes
she suggested genetic elements are capable of moving
Barbara Mcclintock
Other term of jumping genes, and its mobile genetic element
Transposition, transposable elements
use RNA intermediate which produces complimentary DNA via diverse transcriptase
Retrotransposons
