Central Nervous System Flashcards

(93 cards)

1
Q

Z drugs are used for

A

Insomnia

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2
Q

Drugs which belong to to 1st type of drugs based on metabolism
I: CYP3A4
II: Glucuronid action

A

Diazepam
Clorezepam
Chlordiazepoxide
Quazepam
Flurazepam

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3
Q

2nd type of drugs according to metabolism in which
I: CYP3A4
II: Faster Glucuronidation

A

Triazolam
Midazolam

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4
Q

3rd type of drugs according to metabolism
II: Direct Glucuronidation

A

Lorazepam
Temazepam
Oxazepam
Estazolam

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5
Q

Anti-epileptic drugs

A

Lorazepam
Diazepam

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6
Q

Drug of choice for status epilepticus

A

Lorazepam

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7
Q

Drug used to treat Juvenile myoclonic seizure
Absence seizure
Infantile spasm

A

Clonazepam

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8
Q

Drugs used to treat partial seizure

A

Clorazepate

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9
Q

Drug used to treat Lennox Gastaut syndrome and Dravet syndrome
Febrile seizures

A

Clobazam

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10
Q

BZDs used intranasal to treat acute repetitive seizure, crescendo seizure

A

Clonazepam
Midazolam

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11
Q

Drug of choice for treatment and prophylaxis of febrile seizures at home

A

Rectal Diazepam

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12
Q

Drugs (BZD) used for Insomnia

A

Quazepam
Flurazepam
Estazolam
Temazepam
Triazolam

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13
Q

Drugs (BZD) used for anxiety treatment are

A

Diazepam
Clorazepate
Chlorodiazepoxide
Alprazolam

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14
Q

Drug used to treat anxiety which given night before surgery

A

Alprazolam

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15
Q

Which drug (BZD) used for muscle relaxant

A

Diazepam

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16
Q

Which drug (BZD) is used for giving analgesia intrathecally

A

Midazolam

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17
Q

Which BZDs are used for alcohol and withdrawal symptoms

A

Diazepam
Clorazepate
Chlordiazepoxide

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18
Q

Which drug is preffered for alcohol and withdrawal symptoms if patient has seizures

A

Diazepam

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19
Q

Which drug (BZD) is preferred for alcohol and withdrawal symptoms

A

Chlordiazepoxide

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20
Q

Which tasteless drug is used as date rape drug
(It is also mixed with beer)

A

Flunitrazepam

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21
Q

Which drug (BZD) is used by drug abusers and also known as roofie

A

Flunitrazepam

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22
Q

Which BZD inverse agonists inhibit GABA action and are convulsants

A

Dimethoxy-ethyl-carbomethoxy-beta-carboline (DMCM)

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23
Q

Which drug BZD-antagonist blocks sedative action of BZDs as well as the convulsant action of DMCM

A

Flumazenil

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24
Q

Which drug type is used in treating spasticity from multiple sclerosis and cerebral palsy

A

BZD

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25
Which drug (BZD) also gave analgesic effect on IV use
Diazepam
26
Which drug is given I.V. in Status Epilepticus
Lorazepam
27
Which drug (BZD) prevent stress ulcers
Diazepam
28
Which drugs (BZD) have no active metabolites
Lorazepam Estazolam Oxazepam
29
Which drug (Barb) is drug of choice for treatment of seizures in neonates
Phenobarbital
30
Which drug is drug of choice for Crigler-Najjar Syndrome type II
Phenobarbital
31
Which melatonin agonist is used for sleep induction and jet lag
Ramelteon
32
Which melatonin agonist is used for treatment of resistant depression
Agomelatine
33
Which melatonin agonists is used to treat sleep awake disorder in blind people
Tasimelton
34
Which melatonin agonists is used in treatment of paradoxical seizures caused by BZDs or Barbiturates
Chloral Hydrate
35
Which drug is drug of abuse used to make Mickey Finn cocktail where it is known as knock out drops
Chloral hydrate
36
Which drugs is a prodrug of meprobamate is used as a muscle relaxant and as an anxiolytic
Carisprodol
37
Which drug (BZD) has residual effects and culminates leading to ingestion peaking after 3-5 days. It is suitable for patients who have frequent nocturnal awakenings, but not for the elderly due to risk of next day sedation, ataxia and mental confusion
Flurazepam
38
Which drug (BZD) is broad spectrum for anxiolytic, muscle relaxant, premedicant, anesthetic and for emergency control of seizures. It is used for sleep maintenance and has less likely rebound insomnia on discontinuation
Diazepam
39
The drug (BZD) used for anxiety disorders and night-time hypnotic It has marked withdrawal phenomena after regular use
Alprazolam
40
Which type of drugs are contraindicated in patients of sleep apnoe and COPD as it aggravates the situation
All hypnotics
41
Which drug is calming amnesic analgesic used in electrical cardioversion of arrhythmias, cardiac catherization, endoscopic in obstetrics
Diazepam
42
Which is the preferred ultra-short acting Barbiturate used as intravenous anesthetic agent used for induction or maintenance
Thiopentone
43
Which ultra-short acting Barbiturate is used in electroconvulsive therapy
Methohexital
44
Name the drugs which are short acting Barbiturates used as pre-anesthetic medication
Butobarbital Secobarbital Pentobarbital
45
Which drug which is a Barbiturate used as third line drug in status epilepticus
Phenobarbital
46
Name the drugs preferred to BZD for treating insomnias
Z-drugs Zolpidem Zaleplon Zopiclone Eszopiclone
47
Which drug type is first line for jet lag and sleep induction in elderly people
Melatonin Agonists
48
Which new type of drugs are being used for sleep maintenance
Dual orexin receptor antagonists (DORAs)
49
Name drugs which are DORA used in sleep maintenance
Suvorexant Daridorexant Lemborexant
50
Melatonin agonists which are contraindicated in younger patients since they lead to galactorrhea, infertility and amenorrhea due to increased prolactin than LH
Tasimelton Ramelteon
51
Which is the shortest acting benzodiazepine
Remimazolam
52
Drug of choice for insomnia in blind people is
Tasimelteon
53
Which general anaesthetic selectively inhibits excitatory NMDA receptors
Ketamine
54
Malignant hyperthermia is a rare complication of use of the following anaesthetic:
Halothane
55
Which type of drugs are listed in Beers List for medications to avoid in elderly due to dizziness, postural instability, ataxia and falls
Z-drugs
56
Which drug is drug of choice in hyperprolactinemia in planning pregnancy
Bromocriptine
57
Which drug is drug of choice in hyperprolactinemia
Pergolide Cabergoline
58
Which type of drug is drug of choice for compulsive behaviour like gambling
Non-Ergot Alkaloids
59
Which drug is drug of choice for suicidal tendency in case of psychosis
Clozapine
60
Which drug is drug of choice for suicidal tendency in case of mania or depression
Lithium
61
Which is treatment of choice for suicidal tendency
Electroconvulsive therapy
62
Which anti-psychotic causes QT prolongation maximum
Ziprasidone
63
Which anti-psychotic causes QT prolongation minimum
Sertindol
64
Which drug is drug of choice for levodopa induced psychosis
Pimavanserin
65
Which drug in Atypical anti-psychotics is most potent D2 blocker
Risperidone
66
Which drug in atypical anti-psychotics are least potent D2 blocker
Clozapine
67
Which drug in atypical anti-psychotics are least potent other receptor blocker
Risperidone
68
Which drug in atypical anti-psychotics are most potent other receptor blocker
Clozapine
69
Which type of anti-psychotics do not have other receptor side effects and weight gain
Third generation Aripiprazole Brexipiprazole Cariprazine
70
Which drugs are drug of choice for tardiness dyskinesia
Valbenazine Deutetrabenazine
71
Which drug is drug of choice for Neuroleptic Malignant Syndrome
Dantrolene
72
Which Kappa receptor agonist has been approved for anti-pruritic effect With chronic kidney disease patients on dialysis
Difelikefalin
73
Which semi-synthetic opoid has been used for GIT, Urethra and Biliary spasm
Papaverine
74
Which drug is drug of choice for prophylaxis of mania
Lithium
75
Which type of drugs are drug of choice in acute mania
Atypical Antipsychotics
76
Which drug is drug of choice in BPD
Lithium
77
Which type of drug and preferred drug for mania in pregnancy
Atypical Anti-psychotics Apiprazole
78
Which drug is drug of choice for TCA toxicity
Sodium Bicarbonate
79
Which two novel drugs are used in resistant Depression but do not cause erectile dysfunction
Vortioxetine Vilazodone
80
Which drug is drug of choice for partial seizure
Carbamazepine
81
Which drug is drug of choice for Generalised seizures in CCB
Sodium Valoproate
82
Which drug worsens JME
Phenytoin and Carbamazepine
83
Which drug is drug of choice of GTCS
Valproate
84
Which drug is drug of choice of JME
Valproate
85
Which drug is drug of choice for Dravet Syndrome
Valproate
86
Which drug is drug of choice for rapid cyclers
Valproate
87
Which drug is drug of choice of Lennox-Gastaut syndrome
Valproate
88
Which drug is drug of choice for atypical absence seizures
Valproate
89
Which drug in epilepsy is most teratogenic
Valproate
90
Which drug is drug of choice for typical absence seizure
Ethosuximide
91
Which drug is drug of choice in partial seizures
Carbamazepine
92
Which drug is drug of choice in trigeminal neuralgia
Carbamazepine
93
Which drug of epilepsy is most preferred for migraine prophylaxis
Topiramate