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Mark's PEARLS > Central Nervous System > Flashcards

Central Nervous System Flashcards

(57 cards)

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1
Q

Sedative Hypnotic:

acute anxiety attacks
anesthesia induction
perioperative sedation

A

Midazolam (short acting)

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2
Q

Sedative Hypnotics

seizure disorders (status epilepticus)
alcohol withdrawal
tranquilizer

A

Diazepam (Long acting)

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3
Q

Sedative Hypnotics

Date-rape drug

A

Flunitrazepam

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4
Q

Sedative Hypnotics

antidote to benzodiazepine overdose

A

Flumazenil

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5
Q

Sedative Hypnotics

anesthesia induction
lethal injection
truth serum

A

Thiopental

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6
Q

Sedative Hypnotics

seizure disorders in children and pregnant

SE: precipitates porphyria, potent inducer of CYP450

A

Phenobarbital

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7
Q

Sedative Hypnotics:

Anticonvulsant maintenance

A

Clonazepam

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8
Q

Sedative Hypnotics

Status epilepticus

A

Lorazepam

Diazepam

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9
Q

Sedative Hypnotics

skeletal muscle relaxation (cerebral palsy)

A

Diazepam

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10
Q

Sedative Hypnotics

panic disorders and phobias

A

Alprazolam

Clonazepam

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11
Q

Sedative Hypnotics

For insomnia

A

Estazolam
Flurazepam
Triazolam

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12
Q

Sedative Hypnotics

anesthesia induction

A

Midazolam

Diazepam

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13
Q

Sedative Hypnotics

Bipolar disprder

A

Clonazepam

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14
Q

Sedative Hypnotics

alcohol withdrawal

A

Chlordiazepoxide

Diazepam

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15
Q

What abnormal sleep pattern results from the use of benzodiazepines?

A

Decreased REM sleep

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16
Q

Which benzodiazepine has the longest half-life?

A

Chlordiazepoxide

longest half-life

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17
Q

Which drugs are considered as Date-rape drugs?

A

Alcohol (Most common)
Flunitrazepam (rohyphol)
Gamma-hydroxybuterate

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18
Q

Shortest acting Sedative hypnotic

Truth serum
Lethal injection

A

Thiopental

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19
Q

What is the most catastrophic symptom of sedative-hypnotic withdrawal?

A

Rebound suicide

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20
Q

Sedative Hypnotics:

For Sleep disorders

A

Zolpidem
Zaleplon

zzzzzzzz (sleep)

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21
Q

ALCOHOL:

Most-frequently abused drug

Overdose: Wernicke-korsakoff syndrome
Withdrawal: delirium tremens

A

Ethanol

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22
Q

ALCOHOL:

Prevention of Wernicke-korsakoff syndrome

A

Thiamine (B1)

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23
Q

ALCOHOL:

Treatment of alcohol withdrawal

Study These Flashcards
A

Diazepam

Chlordiazepoxide

24
Q

ALCOHOL:

Wood alcohol

SE: visual dysfunction due to formaldehyde accumulation

25
ALCOHOL: Anti-freeze SE: nephrotoxicity due to oxalic acid accumulation
Ethylene glycol
26
ALCOHOL: Alcohol dehydrogenase inhibitor
Fomepizole
27
ALCOHOL: Aldehyde dehydrogenase inhibitor
Disulfiram
28
Anti seizure drug: Status epilepticus potent CYP450 inducer Narrow therapeutic window SE: Gingival Hyperplasia, hirsutism, fetal hydantoin syndrome
Phenytoin
29
Anti seizure drug: potent CYP450 inducer DOC for partial seizures and trigeminal neuralgia SE: Blood dyscrasia, auto inducer
Carbamazepine
30
Anti seizure drug: potent CYP450 inhibitor DOC for GTC and myoclonic seizures SE: teratogen (spina bifida)
Valproic acid *Only CY P450 INHIBITORS
31
Anti seizure drug: potent CYP450 inducer DOC for Seizures in children and pregnant women SE: porphyria
Phenobarbital For pregnant patient: - phenobarbital - lamotrigine - leviteracetam
32
Anti seizure drug: DOC for absence seizure SE: behavioral changes
Ethosuximide
33
Anti seizure drug: DOC for status epilepticus SE: anterograde annesia
Diazepam
34
Anti seizure drug: Treatment of neuropathic pain SE: Nystagmus, tremor
Gabapentine
35
Anti seizure drug: For pregnant women SE: SJS
Lamotrigine
36
ANTI SEIZURE: DOC for General tonic-clonic seizures
Valproic acid Phenytoin Carbamazepine Lamotrigine
37
ANTI SEIZURE: DOC for Partial seizures
Carmazepine Lamotrigine Phenytoin
38
ANTI SEIZURE: DOC for Absence seizures
Ethosuximide | Valproic acid
39
ANTI SEIZURE: DOC for Myoclonic and Atypical Absence Syndromes
Valproic Acid
40
ANTI SEIZURE: DOC for Status epilepticus
Lorazepam Diazepam Phenytoin Phenobarbital
41
ANTI SEIZURE: Status epilepticus potent CYP450 inducer SE: Gingival Hyperplasia, hirsutism, fetal hydantoin syndrome
Phenytoin
42
SEDATIVE HYPNOTIC POISONING
Hot Hot Hot DeCisioN! ``` Hypothermia Hypotension Hypoactive BS Disinhibition Coma Nystagmus ```
43
ANTI SEIZURE: First line for MANIA
Valproic acid Others: carbamazepine, lanotrigine
44
ANTI SEIZURE: Trigeminal neuralgia
Carbamazepine
45
ANTI SEIZURE: Migraine
Gabapentin Phenytoin Topiramate
46
Anti seizure drug that is a potent CYP450 inducer, DOC for partial seizures and trigeminal neuralgia SE: Blood dyscrasia, auto inducer
Carbamazepine
47
Anti seizure drug that is a potent CYP450 inhibitor, DOC for GTC and myoclonic seizures SE: teratogen (spina bifida)
Valproic acid
48
Anti seizure drug that is a potent CYP450 inducer, DOC for Seizures in children and pregnant women SE: porphyria
Phenobarbital
49
Anti seizure drug used as DOC for absence seizure | SE: behavioral changes
Ethosuximide
50
Anti seizure drug used as DOC for status epilepticus | SE: anterograde annesia
Diazepam
51
Anti seizure drug used as Treatment of neuropathic pain | SE: Nystagmus, tremor
Gabapentine
52
Anti seizure drug used for pregnant women | SE: SJS
Lamotrigine
53
DOC for General tonic-clonic seizures
Valproic acid Phenytoin Carbamazepine
54
DOC for Partial seizures
Carmazepine Lamotrigine Phenytoin
55
DOC for Absence seizures
Ethosuximide | Valproic acid
56
DOC for Myoclonic and Atypical Absence Syndromes
Valproic Acid
57
DOC for Status epilepticus
Lorazepam Diazepam Phenytoin Phenobarbital

Mark's PEARLS (24 decks)

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