Cephalosporins Part 1 Flashcards Preview

01. Antimicrobials > Cephalosporins Part 1 > Flashcards

Flashcards in Cephalosporins Part 1 Deck (18):
1

1st Gen Cephalosporins

Cefazolin, cephalexin,

2

1st Gen Ceph Spectrum

Good: MSSA, strep
Mod: some enteric GNR

3

Cefazolin Dosing

IV/IM: 1-3 g q6-8h, max/day: 12 g

4

Cefazolin Renal

35-50: q8h, 11-34: half q12h, 0-10: half q18h

5

Cephalexin Dosing

PO: 250-1000 mg q6h, max/day: 4 g

6

Cephalexin Renal

15-29: 250 mg q8h; 5-14: 250 mg q24h; 1-4: 250 mg q48h

7

2nd Gen Cephalosporins

Cefuroxime, cefoxitin

8

2nd Gen Ceph Spectrum

Good: some enteric GNRs, H flu, Neisseria
Mod: strept, staph, anaerobes (cefoxitin)

9

Cefuroxime Dosing

IV/IM/PO: 250-1500 mg q8-12h

10

Cefuroxime Renal

10-30: q24h, 0-10: q48h

11

Cefoxitin Dosing

IV: 1-3 g q4-8h, max/day: 12 g

12

Cefoxitin Renal

30-50: 2 g q8h, 10-29: 2 g q12h, 5-9: 1 g q12h, 0-5: 1 gm q24h

13

Ceph Combo

Ceftazidime/avibactam; cefolozane/tazobactam

14

Ceph Combo Spectrum

Good: enteric GNRs, B. fragilis, strep, Pseudomonas

15

Ceftolozane/tazobactam Dose

IV: 1.5 g q8h

16

Ceftolozane/tazobactam Renal

30-50: 750 mg; 15-29: 375 mg

17

Ceftazidime/avibactam Dose

IV: 2.5 g q8h

18

Ceftazidime/avibactam Renal

31-50: 1.25 g q8h, 16-30: 0.94 g q12h, 6-15: 0.94 g q24h, 0-5: 0.94 g q48h