Cephalosporins Part 2 Flashcards Preview

01. Antimicrobials > Cephalosporins Part 2 > Flashcards

Flashcards in Cephalosporins Part 2 Deck (18):
1

3rd Gen Ceph

Ceftriaxone, cefotaxime, ceftazidime, cefdinir, cefpodoxime

2

3rd Gen Ceph Spectrum

Good: strept, enteric GNRs, Pseudomonas (ceftazidime only)
Mod: MSSA (not ceftazidime)

3

Ceftriaxone Dose

IV/IM: 1-2 g q12-24h; no renal

4

Cefotaxime Dose

IV/IM: 1-2 g q4-12h

5

Cefotaxime Renal

0-20: half

6

Cefdinir Dose

PO: 300 mg BID or 600 mg Daily

7

Cefdinir Renal

0-30: 300 mg daily

8

Ceftriaxone Cautions

Crystallizes with calcium, biliary sludging in neonates

9

Cefpodoxime Dosing

PO: 100-400 mg q12h

10

Cefpodoxime Renal

0-30: q24h

11

Ceftazidime Dosing`

IV/IM: 1-2 g q8h

12

Ceftazidime Renal

31-50: 2 g q12h, 16-30: 1 g q12h, 6-15: 1 q24h, 0-5: 500 mg q24h

13

Ceftaroline Spectrum

Good: MSSA, MRSA, strepto, enteric GNRS
Mod: E. faecalis

14

Ceftaroline Dosing

IV: 600 mg q12h

15

Ceftaroline Renal

31-50: 400 mg, 15-30: 300 mg, 0-15: 200 mg

16

Cefepime

Good: MSSA, strept, Pseudomonas, enteric GNRs
Mod: Acinetobacter

17

Cefepime Dose

IV/IM: 1-2 g q8-12h

18

Cefepime Renal

30-60: 2 g q12h, 11-29: 2g q24h, 0-11: 1 gm q24h