Cerebellum Flashcards

(85 cards)

1
Q

Cerebellum

A

integrates massive sensory and other inputs from the brain and spinal cord

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2
Q

cerebellum participate in

A

motor planning

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3
Q

cerebellum relationship with LMNs

A

no direct connection

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4
Q

cerebellum is found in

A

posterior cranial fossa

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5
Q

cerebellum is covered superiorly by

A

tentorium cerebelli = infratentorial

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6
Q

cerebellum is posterior to what structures

A

4th ventricle
pons
upper medulla

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7
Q

cerebellum is connected to the post aspect of the brainstem by

A

sup, mid, and inf cerebellar peduncles

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8
Q

cerebellum form what structure

A

roof of 4th ventricle

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9
Q

deepest fissure of cerebellum

A

primary fissure

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10
Q

what fissure separates anterior and middle (POST) lobe

A

primary fissure

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11
Q

fissure that separates the middle lobe from flocculonodular lobe

A

uvulonodular fissure (posterolateral fissure)

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12
Q

along the margin of the cerebellum that separates the superior from inferior surfaces

A

horizontal fissure

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13
Q

3 main lobes of cerebellum

A

anterior lobe, middle (post) lobe, fiocculonodular lobe

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14
Q

on the superior surface and separated from middle (post) lobe by the primary fissure

A

anterior lobe

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15
Q

largest lobe

A

middle (posterior) lobe

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16
Q

lobe between the primary and uvulonodular fissure

A

middle (post lobe)

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17
Q

herniate through the foramen magnum in cases of increased intercranial pressure

A

cerebellar tonsil

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18
Q

cerebellar tonsil herniation cause death via compression of

A

medullary respiratory centers

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19
Q

3 functional subdivisions

A

vermis, flocculonodular lobe, cerebellar hemispheres

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20
Q

influences movement of long axis of the body (neck, shoulder, thorax, abdomen,a nd hips)

A

vermis

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21
Q

balance and vestibulo-ocular reflex

A

flocculonodular lobe

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22
Q

zones of cerebellar hemisphere

A

intermediate and lateral zone

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23
Q

immediately lateral to the vermis; control muscles of distal part of limbs

A

intermediate zone

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24
Q

planning of sequential movements of entire body; conscious assessment of movement occurs

A

lateral zone

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25
functions of each functional division of the cerebellum
lateral hemispheres - motor planning for extremities intermediate hemispheres - distal limb coordination Vermis - proximal limb and trunk coordination flocculonodular lobe - balance and vestibulo-occular reflexes
26
gray and white of cerebellum
outer gray (cortex), inner white
27
small ridges that run from medial to lateral surface of the cerebellum (leaves)
folia
28
3 layers (outer to inner)
molecular layer purkinje cell layer granular layer
29
molecular layer contains what cells
stellate (outer) basket (inner)
30
purkinje cell layer contains what type of neuron
large golgi type 1 neuron
31
flask-shaped, arranged in a single layer
purkinje cell layer
32
describe branches of purkinje cell layer
primary, secondary are smooth subsequent are covered by short thick dendritic spines
33
purkinje cell layer terminates by synapsing with
intracerebellar nuclei
34
small cells with densely staining nuclei and scanty cytoplasm
granular cell
35
each granular cell gives rise to how many dendrites
4-5
36
axons of granular cell pass through molecular layer and bifurcates at
T junction
37
branches running parallel to the long axis of the folium run at right angles to the dendritic processes of the purkinje cells synapse with spinous process of dendrites of purkinje cells
parallel fibers
38
dendrites ramify in molecular layer and axons terminate with dendrites of granular cells
golgi cells
39
intracerebellar nuclei consist of (lat to med)
Dont Eat Greasy Food Dentate Emboliform Globose Fastigial
40
composed of large, multipolar neurons with branching dendrites
intracerebellar nuclei
41
receive collateral fibers of cerebellar inputs on their way to the
cerebellar cortex
42
all outputs from cerebellum are relayed by
cerebellar nuclei
43
largest intracerebellar nuclei
dentate nucleus
44
interior of dentate nucleus is filled with white matter efferents that leave the nucleus to form
superior cerebellar peduncle
45
dentate nucleus receive projections from
lateral cerebellar hemisphere
46
dentate nucleus is active when
before voluntary movement
47
ovoid shape and medial to the dentate
emboliform nucleus
48
consists of one or more rounded cell groups medial to the emboliform nucleus
globose
49
emboliform and globose is collectively known as
interposed nuclei
50
interposed nuclei (emboliform and globose) receive input from
intermediate part of cerebellar hemisphere
51
interposed nuclei (emboliform and globose) is active when
during and in relation to movement
52
intracerebellar nuclei that is close to the roof of 4th ventricle
fastigial nucleus
53
fastigial nucleus receive input from
vermis (more) and flocculonodular lobe
54
white matter in vermis and cerebellar hemisphere
small amount in vermise, increase in cerebellar hemisphere
55
group of white matter that doesnt leave cerebellum and connects different regions within the organ
intrinsic
56
greater group of white matter which proceed to cerebellar cortext
afferent
57
output group of white matter
efferent
58
efferent group starts off as
axons of purkinje
59
cerebellar peduncles
superior cerebellar peduncle = brachium conjunctivum Middle = brachium pontis Inferior = resitiform body
60
cerebellar peduncles decussates at the level of
inferior colliculi
61
cerebellar peduncle inputs what
superior - output from cerebellum middle and inferior - input
62
2 kinds of synaptic inputs to cerebellum
climbing fibers mossy fibers
63
synaptic inputs to cerebellum are excitatory to
purkinje fibers
64
terminal fibers of olivocerebellar tract
climbing fibers
65
1 climbing fiber:
10 purkinje cells
66
1 purkinje cell:
1 climbing fiber
67
arise from numerous origins terminal fibers of all other cerebellar afferent tracts
mossy fibers
68
1 mossy fiber:
thousand of purkinje cells through granule cells
69
other cells of cerebellar cortex (inhibitory interneurons)
stellate basket golgi
70
center of a functional unit of cerebellar cortex
purkinje cells
71
stellate cells terminate on
purkinje cell dendrites
72
basket cells terminate on
purkinje cell body
73
receive excitatory inputs from the granule cell paralell fibers in the molecular layer shorten the durtion of excitatory inputs to the granule cell
golgi cell
74
excited by synaptive inputs from granule cell then give rise to processes that run in rostro caudal direction, perpendicular to the parallel fibers lateral inhibition of adjacent purkinje cells and narrow the spatial extent of excitatory inputs to purkinje cells
stellate and basket
75
In intracerebellar nuclear mechanisms, afferents come from
inhibitory axons of purkinje cells excitatory aoxns from climbinga nd mossy fibers passing to the cortex
76
cerebellar cortical NT
Glutamate - excitatory; climbing and mossy fibers to dendrites of purkinje cells Norepinephrine and serotonin- modify the action of glutamate on purkinje cells
77
rough somatotopic organization, with ipsi body represented in both anterior and posterior lobes
cerebellar input pathways
78
cerebellar input pathways is carried by
mossy fibers and climbing fibers (olivocerebellar fibers)
79
pathways from cerebral cortex
corticopontocerebellar cerebro-olivocerebellar cerebroreticulocerebellar
80
cerebral cortex control what
voluntary movement monitor and adjust muscle activity
81
pathway that gives rise to mossy fiberd
corticopontocerebellar pathway
82
spinocerebellar fibers from spinal cord
anterior (ventral) spinocerebellar tract posterior (dorsal) cuneocerebellar rostral spinocerebellar
83
functions of spinocerebellar tracts
Anterior spinocerebellar - convey info from MS, Tendon organs, and joint receptors of UE and LE Posterior - trunk and LE cuneocerebellar - UE and neck Rostral spinocerebellar (least well characterized) - Vestibulocerebellar fibers - info about position of head and body in space - orienting the eyes during movement
84
main outflow from cerebellum
axons from cerebellar nuclei
85