Cerebellum Flashcards

1
Q

In order to accomplish the functions of the cerebellum, the cerebellum must have (2 things)

A
  1. reciprocal interactions with motor regions of the CNS

2. integration with sensation with motor signals

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2
Q

T/F

a cerebellar lesion of loss of function leads to a paralysis or loss of sensation

A

FALSE

It leads to an inability to move in a smooth and coordinated manner

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3
Q

What are two non motor functions of the cerebellum?

A

Cognitive functions: memory, language, visual spatial processing

Emotional Regulation: affect, behavioral regulation and mood

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4
Q

What are the three lobes of the cerebellum?

What is each lobe associated with?

A

Anterior-spinal cord input-proprioceptive input
Posterior-cortex
Flocculonodular- vestibular input

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5
Q

T/F Output from the Cerebellum to other CNS structures can come from the deep nuclei, OR the cortex of the cerebellum.

A

False!!!
Output can only come from deep nuclei,

Input can go to either the cortex of the cerebellum OR the nuclei

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6
Q

T/F The inferior and middle peduncles of the cerebellum are pathways for afferent information

A

True.
Inferior and middle=input
superior=output

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7
Q

The spinocerebellar pathways project from _____ peduncle, to which two lobes of the cerebellum

A

Inferior peduncle

anterior and posterior lobes

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8
Q

T/F vestibular inputs to the cerebellum come directly from the vestibular receptors ONLY.

A

False.

Directly from receptors AND indirectly from vestibular nuclei

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9
Q

What information is gathered from vestibular inputs?

A

Head position in space

status of extensor motor neurons

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10
Q

Which cerebellar lobes does the reticular formation project to?

A

Vermal regions of the anterior and posterior lobe

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11
Q

T/F The reticular projections provide integrated information from the cortex and cord

A

True:

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12
Q

What type of infomation comes from the reticular formation to the cerebellum?

A

Mediates extensor tone

coordination of movement, balance, and equilibrium

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13
Q

Tectal projections to the cerebellum give us what infomration?

A

Visual and auditory input

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14
Q

Trigeminal nucleus to the cerebellum gives us what information

A

proprioceptive info of the face

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15
Q

What are the three types of internal fibers?

A

Mossy
Climbing
Purkinje

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16
Q

These fibers provide sensory and motor input; arise from all inputs except those from inferior olive

A

Mossy fiber

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17
Q

This fiber type provides output from the cerebellar cortex. They drive specific movements

A

Purkinje fiber

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18
Q

This fiber projects from the inferior olive; synapses on purkinje cells

A

Climbing fiber

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19
Q

This fiber is thought to be responsible for guiding encoding of new stimulus-response links

A

Climbing fiber

20
Q

This fiber gets outputting information from the cerebellar nuclei

A

Purkinje

21
Q

These two fibers receive inputting information

A

Mossy and climbing fibers

22
Q

What are the three layers of the cerebellar tissue?

A

Granular
Molecular
Purkinje

23
Q

What are the two types of cerebellar cells?

A

Interneurons (granular, golgi, stellate)

Purkinje cells

24
Q

This cell receives output from cerebellar cortex and is inhibitory

A

Purkinje cells

25
Q

This fiber is excitatory and receives widespread input from the cord, reticular formation, vestibular system and pons

A

Mossy fiber

26
Q

This fiber projects to deep cerebellar nuclei and granule cells

A

Mossy fibers

27
Q

This fiber receives diverse input and keeps record of ongoing activity constantly. It provides background information

A

Mossy fiber

28
Q

This fiber is associated with efferent monitory “corollary discharge”

A

Mossy fiber

29
Q

This fiber is excitatory and receives input from the inferior olive

A

Climbing fiber

30
Q

This fiber projects to deep cerebellar nuclei and purkinje cells at a 1:1 ratio

A

Climbing fiber

31
Q

This fiber receives cortical input involved in the programming and execution of intended movement

A

climbing fiber

32
Q

Which output influences eye and postural movements and plays a role in equilibruim contral

A

Vestibulocerebellar

33
Q

T/F vestibulocerebellar efferent pathways connect with vestibular nuclei reicprocally

A

True

34
Q

Vestibular nuclei send information to the flocculonodular lobe of the cerebellum which gives input to which deep nucleus

A

Fastigial

Which then sends input back to the vestibular nuclei

35
Q

Which two nuclei make up the interposed nucleus?

A

Globose and Emboliform

36
Q

Trace the input pathway from cortical input to the interposed nucleus

A

Red nucleus->interior olive->anterior/posterior lobe_> interposed nucleus

37
Q

T/F Interposed nuclei mediate cervical flexors

A

True

38
Q

This nucleus is triggered by sensory cues in the environment. Signals direction of movement and joint position and relays information to motor cortex to adjust timing, intensity and velocity

A

Dentate nucleus

39
Q

Where does the dentate nucleus recieve input from?

A

Cortical input-> pontine nucleus–>cerebellar hemispheres==> dentate nucleus

40
Q

Where does the dentate nucleus send information?

A

VL thalamus–>motor cortex

41
Q

Ataxia is a observable issue with which part of the cerebellum?

A

Floculonodular lobe

and vermal region of the anterior or posterior lobe

42
Q

Ataxia is characterized by what movements?

A

Wide, slow gait

Tendency to fall toward side of lesion

43
Q

Hypotonia may be an observation of problems in which part of the cerebellum?

A

Vermal or paravermal region

We don’t really fuckin’ know.

44
Q

Dysarthria and cerebellar nystagmus is associated with issues in which part of the cerebellum?

A

Vermal lesions

45
Q

The inferior olive recieves input from which two things?

A

Red nuclues “cortico-rubro-olivary fibers (sensorimotor)
And
Spinal cord fibers

46
Q

From the inferior olive, trace the infomration pathway

A

Inferior peduncle
spinocerebellar fibers go to anterior lobe
cerebrocerebellar fibers go to posterior lobe