Ch 10 - Peds: CTD, Burns, Cancer Flashcards
What is the MC connective tissue disorder in children?
Juvenile RA
Describe Iridocyclitis in pauciarticular type I RA.
50% chronic
Describe Iridocyclitis in pauciarticular type II RA.
10-20% acute
Describe HLA studies in pauciarticular type II RA.
HLA-B27
Why is ASA not used in children?
Risk of Reye’s syndrome with influenza and varicella infections
What are approved NSAIDs for children?
Naproxen
Ibuprofen
Tolmetin
What joints are involved in JRA?
Cervical spine (AA joint) TMJ 50% Shoulder Elbow Wrist Hand Hips 50% of polyarticular JRA Knee Ankle/foot
What are the clinical features of Juvenile Dermatomyositis?
Histologic presence of vasculitis
Onset of calcinosis
No association with malignancy in childhood
MC girls 5-14 yo
What is Morphea?
Localized form of scleroderma that is limited to skin
Small lesions occur with minimal sclerosis (guttate morphea)
Self-limiting: 2 to 3 years
What are the Major Jones Criteria for Rheumatic fever?
Carditis Polyarthritis Chorea Erythema marginatum Subcutaneous nodules
What are the Minor Jones Criteria for Rheumatic fever?
Fever
Arthralgia
Inc ESR or CRP
Prolonged PR interval
What is needed to diagnose Rheumatic fever?
2 of the major criteria, or 1 major and 2 minor criteria, are required for diagnosis with evidence of preceding streptococcal group A infection
What is the hallmark of hemophilia?
Hemarthrosis
What is Kawasaki’s disease?
Infantile polyarteritis
Systemic vasculitis in <4 yo
What are diagnostic criteria for Kawasaki’s disease?
- High grade fevers >5 days
- Strawberry tongue
- Bright red, chapped lips
- Pharyngeal erythema
- Conjunctival injection
- Edema of the hands or feet
- Erythema of the palms or soles with desquamation in later stages
- Truncal rash
- Cervical lymphadenopathy
