Ch 12 Flashcards Preview

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Flashcards in Ch 12 Deck (15):
1

anergy

no reaction

2

PAH

polycyclic aromatic hydrocarbons

3

hygiene hypothesis

lack of exposure to common pathogens at a young age make the person susceptible to them as an adult
not supported by data at all

4

mast cell degranulation causes

GI- expulsion, vomiting and diarrhea
eyes, nasal passages, airways- congestion, blockage, swelling
blood vessels- increased blood flow and lymph

5

spasms of smooth muscle in bronchi

asthma

6

H1- immuno, vaso muscle; H2- mucous, secretion (drowsy)

antihistamines

7

epinephrine, increase cAMP production
beta 1- heart
beta 2- smooth muscle of bronchi/bronchodilators

catecholamines

8

increase cAMP

theophylline

9

blocks Ca2+ channels

cromolyn

10

inhibit synthesis of LTs and PGs

steroids (local)

11

Singulair

anti-leukotrienes

12

anti-IL-5

inhibit eosinophils

13

prolonged exposure to increasing amounts of allergen

desensitization

14

injections of allergen

cause IgG to increase, IgE to decrease, release IL-10

15

phagocyte tries to engulf tissue or something too large

frustrated phagocytosis