Ch 7 Malaria

Question 1

What mosquito transmits malaria?

Answer 1

Female Anopheles

Question 2

Malaria parasite

Answer 2

Plasmodium

Question 3

Injected into human when bitten

Answer 3

Sporozites

Question 4

Sporozoites enter parenchymal cells of liver to become:

Answer 4

Schizonts

Question 5

Development in liver

Answer 5

Pre-erythrocytic cycle

Question 6

Development in liver after RBC invasion

Answer 6

Exoerythrocytic cycle

Question 7

Inside parenchymal cells, Schizonts rupture, releasing _______

These burst out of liver cells to invade RBCs

Answer 7

Merozoites

Question 8

Merozoites develop to form immature (ring stage):

Answer 8

Trophozoites

Question 9

Merozoites feed on:

Answer 9

Hgb

Question 10

Malarial pigment from merozoites is composed of

Answer 10

Hematin and protein

Question 11

Mature trophozoites develop into

Answer 11

Schizonts

Question 12

Schizonts rupture releasing:

Answer 12

Merozoites

Question 13

Derived from merozoites

Differentiation in sexes

Answer 13

Gametocyte

Question 14

What is ingested by the mosquito that starts sexual reproduction?

Answer 14

Gametocyte

Question 15

Beginning of sexual reproduction; production of:

Answer 15

Zygote

Question 16

Fertile zygote excysts, penetrating the midgut wall of the mosquito forming:

Answer 16

oocyst

Question 17

From the mosquito

What matures, ruptures, and releases sprozoites?

Answer 17

Oocyst

Question 18

Mosquito

Sporozoites migrate to the _______, injected into a new host

Answer 18

Salivary gland

Question 19

All stages of the asexual cycle can be demonstrated in a peripheral blood smear with the exception of:

Answer 19

P. Falciparum

Question 20

Only rings and gametocytes:

RBC membrane becomes _______ as parasite matures

Answer 20

Sticky

Question 21

Light blue circular structures with red chromatin dot

Answer 21

Ring form of P. Falciparum

Question 22

Curved sausage/banana shaped with central large chromatin dot covered with centralized mass of hemazoin

Answer 22

Macrogametocyte (FEMALE)

Question 23

Shorter and wider than female with rounded ends, diffused chromatin seen with hemozoin granules

Answer 23

Microgametocyte (MALE)

Question 24

Considered diagnostic

Answer 24

Gametocyte of P. Falciparum

Question 25

Four types of malaria found in humans

Answer 25

Plasmodium Falciparum Plasmodium Vivax Plasmodium Ovale Plasmodium Malariae

Question 26

Most fatal: likely to cause intravascular hemolysis | -Fever is prolonged and intensified

Answer 26

Plasmodium Falciparum

Question 27

Erythrocytic cycle: Malignant tertian

Answer 27

Falciparum

Question 28

Most common Erythrocytic cycle: Benign Tertian

Answer 28

Vivax

Question 29

Erythrocytic cycle: Benign Tertian

Answer 29

Ovale

Question 30

Erythrocytic cycle: Benign Quartan Fever every 3rd day

Answer 30

Malariae

Question 31

Blood collection methods for Malaria

Answer 31

Capillary (EDTA tube from kit) Venous blood (EDTA, purple top)

Question 32

Venous blood sample may be stored for up to

Answer 32

3 days (2 to 30 degrees C)

Question 33

If blood sample is refrigerated, you should:

Answer 33

Allow sample to reach room temperature

Question 34

Rapid Malaria Test materials

Answer 34

Test kit cardboard w/ test strip Reagent A Capillary tubes Lancets (Optional) Venipuncture kit w/ purple top

Question 35

Sample pad

Answer 35

Purple

Question 36

Place the blood collected on purple pad until

Answer 36

Saturated

Question 37

For venipuncture method, collect ___ microliters

Answer 37

15

Question 38

Reagent pad

Answer 38

white

Question 39

Place __ drops of Reagent A on white pad

Answer 39

2

Question 40

If the mixture does not run through the white test strip in ___, add another drop of reagent

Answer 40

1 minute

Question 41

Before the mixture reaches the top of the test strip, add an additional __ drops of reagent strip to the wash pad

Answer 41

4

Question 42

When would you remove adhesive and close the kit?

Answer 42

When mixture reaches the top of the test strip

Question 43

Read results through the viewing area at:

Answer 43

15 minutes

Question 44

Must appear for test to be valid

Answer 44

"C" line

Question 45

T1 is positive for:

Answer 45

Falciparum

Question 46

T2 is positive for:

Answer 46

Vivax Malariae Ovale

Question 47

T1 and T2 is positive for

Answer 47

Falciparum and a mix of other types

Question 48

Indicates the test is negative

Answer 48

Only the "C" line appears

Question 49

Samples must be obtained when the patient is:

Answer 49

Febrile

Question 50

Rapid malaria kit will only detect:

Answer 50

Antigens

Question 51

Test must be confirmed with a thick and thin smear sent to:

Answer 51

NEPMU

Question 52

Cannot be used to monitor treatment progress because:

Answer 52

Residual antigens from the parasite can last several days post elimination

Question 53

False positive results in patients with the following:

Answer 53

Rheumatoid arthritis Chronic viral infections (Hep C) Other blood parasite (Babesia)

Question 54

Smears should be done

Answer 54

Frequently but no more than hourly