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IHP 1001 > CH.5 Epithelial Tissue > Flashcards

CH.5 Epithelial Tissue Flashcards

(55 cards)

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1
Q

3 main structure/functions of the epithelium

A
  1. Avascular
  2. Covers ext surfaces and internal cavities
  3. Creates barrier btwn ext envorment and undelying connecitve tissue
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2
Q

WHat are the 3 principle characteristics of epithelial cells?

A
  1. Close to each other, bind via cell juctions
  2. Exhibit functional and morpholoical polarity
  3. Basal structure attache to basment membrane
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3
Q

one-cell layer, thick rests in basement membrane. (can very in shape)

A

SImple

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3
Q

2 or more cell layers (shape of cell on surface determines its classification

A

Stratfied

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4
Q

width of the cell is greater than its height

A

Squamous

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5
Q

width, depth, and height are approximately the same

A

Cuboidal

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6
Q

– the height of the cell exceeds the width

A

Collumnar

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7
Q

appears stratified. Simple epithelium with all cells resting on basement and not all extend to free epithelia surface.

A

Psudostrasifed

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8
Q

stratified and lines lower part of urinary tracts.

A

Transitional urothelum

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9
Q

Endothelium lines? (2)

A
  1. Blood
  2. Lymphatic vessles
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10
Q

Mesothelium lines? (2)

A
  1. Abdomen
  2. Pleural Cavities
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11
Q

Specialized Epithelial Functions

5 specialized functions of epithelium

A
  1. Secretion (stomach
  2. Absorbtion (intestine & kidney)
  3. Transport (bronchial tree)
  4. Mechanical Protection (epidermis)
  5. Receptor Function (taste buds)
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12
Q

Directed toward the exterior surface or lumen

A

Apical Domain

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13
Q

Communicates with adjacent epithelia

A

Lateral Domain

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14
Q

Anchors cell to the basal lamina

A

Basal Domain

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15
Q

Apical Domain Modifications

Actin Filamint core

A

Microvilli

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16
Q

Apical Domain Modifications

Long microvilli

A

Sterocilia

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17
Q

Apical Domain Modifications

Microtubule Bundle

A

Cilia

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18
Q

Function of microvilli (apical)

A
  1. Increase SA for absorbtion
  2. Intesin & Kidney
  3. Long cytoplasmic processes containing core of actin
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19
Q

?

A

Stereocilia (apical)

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20
Q

Features of Stereocillia

A
  • Long microvillia
  • Absorbtion in male reproductive
  • Sensory hair cell inner ear
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21
Q

Cillia are____ they generate motion via ____

A

Motile, activity of dynein

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22
Q

Cillia are what 3 sensors?

nodal important in embryonic dev

Study These Flashcards
A
  1. Chemosensors
  2. Osmosensors
  3. Mechanosensors

in all euk. cells

23
Q

Primary Ciliary Dyskinesia are?

Study These Flashcards
A

Family of hereditary disorders

24
an absence of **dynein arms** in cilia
Kartageners syndrom
25
malformation of the **radial spokes and dynein arms**
Young's Syndrome
26
What is the most prominant symptom of **PCD**?
**Chronic respirator disorders** like * Bronchitis * Sinusitis | deffective cillia
27
**Specialized for Cell-to-Cell Adhesion** Unique proteins called cell adhesion molecules (CAMs)
Lateral Domain
28
3 types of juntions in the lateral domain?
1. Occluding 2. Anchoring 3. Communicating
29
1. Known as the **Zonula Occludens** 2. Created by **localized sealing** of the plasma membrane between two adjacent cells 3. **Restricts passage of substances btwn cells**.
Occluding Junctions | Tight Junctions
30
* interact with the **actin filaments inside the cell** * Provides lateral adhesion between epithelial cells * E-cadherin catenin complex.
Zona Adherens | Anchoring Junctions
31
interact with **intermediate filaments**
Macula adherens (desmosome) | Anchoring Junctions
32
anchor **actin filaments** into the basement membrane
Focal Adhesions | Anchoring junctions, cell to ECM
33
Anchor **intermediate filaments** into the basement membrane
Hemidesmosomes | Anchoring Cell to ECM
34
Permit direct passage of signaling molecules from one cell to another; **transmembrane channels**
Communicating/ gap junctions
35
Epithelia, smooth/cardiac muscle, and nerves **have what junctions?**
Gap Junctions | Coordinated activity, 2 half channels
36
Gap junctions allow for exchange of
Ions, reg molecules, metabolites etc btwn cells.
37
Proteins called ____ make up **gap junctions** Each channel consists of**12 subunits**
connexin
38
* basment membrane * Cell to ECM junctions occur here
Basal Domain
39
The basment membrane is ____ positive in LM
PAS positive (purple
40
Specialized structure located **next to the basal domain** of epithelial cells and the **underlying connective tissue**
Basmement membrane
41
* Collagens * Laminin * Entactin/nidoge * Proteoglycans are all components of the?
Basment membrane
42
**Important sites of signal detection and transduction** Mechanosensitivity
Focal Adhesions
43
* Provide **increased adhesion to the basal lamina** * Cornea, skin, oral cavity mucosa, esophagus
Hemidesmosomes
44
Cells that transport fluid have ____ which increase SA for more transport protiens and channels to be present
Inflodings
45
Oriention of mitochondria can result in ____ appearance Happens in salivary gland ducts
Straiated appearence
46
Secretion gland? (2)
1. Endocrine 2. Exocrine
47
Singnaling gland (2)
1. Paracrine 2. Autrocrine
48
**mucous or serous (protein rich water)** Secrete products directly onto a surface or through **ducts/tubes** connected to a surface, concentrating, removing waste, adding substances.
Exocrine gland
49
**no ducts** Hormones into blood stream to reach specific receptor on surface of distant cell
Endocrine land
50
Secretory product is delivered in **membrane-bound vesicles** which fuse with the plasma membrane to **release their contents by exocytosis**
Merocrine | Secretion
51
Secretory product is **released in the apical portion** of the cell **surrounded by a thin layer of cytoplasm**
Apocrine | Secretion
52
Secretory product **accumulates within the maturing cell** which simultaneously undergoes **destruction**
Holocrine | Secretion
53
* Very limited signaling range * Reach target cells by **diffusion**
Paracrine
54
* Broad signaling range * Travel through **bloodstream to distant targets**
Autocrine

IHP 1001 (18 decks)

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