Ch.7 (Membrane Structure and Function) Flashcards

1
Q

Properties of Membranes (6)

A

-flexibility
-self-sealing
-fluidity
-can fuse with one another, can bud off vesicles
-exhibit selective permeability
-work like capacitors: opposite charges separate and align for membrane potential

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2
Q

Membrane Prop1. Flexibility

A

membranes can take any shape as long as there is a cytoskeleton or cell wall

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3
Q

Membrane Prop2. Self-sealing

A

Phospholipids of membrane will form enclosed environment. NO OPEN ENDS

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4
Q

Membrane Prop3. Fluidity

A

there are factors that affect fluidity

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5
Q

Factors that affect fluidity (5)

A

-Temperature (higher means more liquid-y)
-Saturation of hydrophobic tails (saturated means solid, unsaturated means more liquid)
-[ONLY ANIMAL] cholesterol levels lower gelling temperature and increase melting temperature
-lateral movements of phospholipids (NO FLIPFLOP movement)
-integral membrane proteins

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6
Q

Membrane Prop4. fuse with each other

A

Endocytic vesicles arise.
Secretory vesicles fuse with PM to release contents to exterior.

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7
Q

Membrane Prop5. selective permeability

A

Easier for cells to maintain homeostasis.

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8
Q

Membrane Prop6. capacitors

A

opposite charges (ions) separate and align along membranes for membrane potential

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9
Q

Membrane associated proteins - integral membrane proteins

A

orientation of membrane associated with proteins within bilayer is asymmetric

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10
Q

Membrane associated proteins - integral membrane proteins - FUNCTIONS (6)

A

-attachement-anchoring proteins (integrin)
-transport: passive and active
-enzymes : synthesis/modifiy fatty acids and metabolic enzymes
-receptors and signal transduction: homeostasis + response to environment
-junctions [gap junctions in animal]
-recognition proteins [antigens]

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11
Q

Transport of small molecules across membrane (5)

A

sugars
ions
water
gases
aa
*NO PROTEINS. NO MACROMOLECULES.

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12
Q

Factors that affect transport (2)

A

-concentration of solutes across membrane
-nature of solutes and water (size and polarity)

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13
Q

Passive Transport (6)

A

-movement of water by osmosis occurs through aquaporins
-water moves from LOW to HIGH
-simple diffusion (HIGH TO LOW)
-facilitated diffusion (HIGH TO LOW)
-no energy required
-diffusion of solute is independent of other solutes

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14
Q

Aquaporins

A

channels which allow water to pass by osmosis (passive)

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15
Q

Paramecium

A

unicellular eukaryote (protist)

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16
Q

What do paramecia use to expel water? Is it passive or active?

A

Active.
Contractile vacuoles.

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17
Q

Simple Diffusion (3)

A

Passive.
HIGH TO LOW
movement of soluble non-polar across membrane

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18
Q

Facilitated Diffusion (3)

A

Passive.
HIGH TO LOW
movement of hydrophilic molecules via channels and transporters

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19
Q

Channels (4)

A

for ions and water
neurons - nervous impulse transmission
direction of transport determined by electrochemical potentials
rapid

20
Q

Transporters (4)

A

for large and polar molecules : sugars and aa
muscle, fat & liver - glucose import
direction of transport determined by chemical potential
slow ; change of shape of transporter involved

21
Q

Hypotonic (2)

A

water moves in
lower external concentration than the solute so water moves in to balance out

22
Q

Isotonic (2)

A

equal concentrations - equilibrium
water moves in and out

23
Q

Hypertonic (2)

A

water moves out
higher external concentration than the solute so water moves out to balance out

24
Q

Which of the three solution conditions is best fit for ANIMAL cells [i.e. red blood cells] ?

25
Which of the three solution conditions is best fit for PLANT cells ?
Hypotonic (called Turgid [firm])
26
Hypotonic - Animal
Lysed (burst)
27
Hypertonic - Animal
Shriveled
28
Hypertonic - Plant
Plasmolyzed
29
Isotonic - Plant
Flaccid
30
Active Transport (2)
Solutes move against their gradients : LOW TO HIGH Requires energy
31
What form of energy is required for active transport? (2)
ATP hydrolysis and/or equivalent
32
Active transport types (3)
Na+/K+ ATPase pumps H+/ATPase pump Electrogenic Pumps
33
Where are Na+/K+ ATPase pumps located?
in PM of animal cells
34
Where are H+/ATPase pumps? (3)
in PM of plant cells across lysosome (animal) vacuole (plant)
35
What are electrogenic pumps?
pump that creates a membrane potential or charge separation across membrane
36
Co-transporters (2) [active transport]
Na+/glucose (animal) H+/sucrose (plant)
37
What are co-transporters also called?
Secondary active transport
38
Bulk transport [definition]
For in and out movement of large macromolecules like proteins in cells
39
Does bulk transport require energy (is it active)?
Requires energy. Active.
40
What is out of cell movement called? [bulk transport] (2)
Exocytosis or secretion
41
What is into cell movement called? [bulk transport]
Endocytosis
42
Exocytosis (3)
uses endomembrane system via fusion of synaptic vesicles with PM (junction of neurons) via fusion of secretory vesicles containing waste with PM (lysosomes, vacuoles)
43
What is the trajectory using the edomembrane system in exocytosis?
RER --> Golgi --> secretory vesicle --> PM
44
Endocytosis (3)
phagocytosis pinocytosis receptor-mediated endocytosis
45
Phagocytosis (3)
cell eating ingestion of large food particles or bacteria involves pseudopod formation by specialized cells (macrophages or immune cells)
46
Pinocytosis (3)
cell drinking drinking of dissolved materials no pseudopods but vesicles pinch off from PM fold
47
receptor-mediated endocytosis
uptake of cholesterol