Chaoter 10 Disease And Immuntuy Flashcards
(12 cards)
Describe pathogen
Disease causing organism
Describe transmissible disease
Disease in which the pathogen can be passed from one host to another
How are pathogens transmitted
Durcect contact - through transfer of blood or body fluids
Indirect - through contaminated surfaces, food ,animals and air
Describe body defences
Mechanical
Skin - prevents infection from pathogen
Hair in the nose- filter out particles that could contain pathogen
Chemical barriers
Stomach acid- contains HCL which kills bacteria
Mucus- traps pathogens which are then moved away
White blood cells
Phagocytosis- engulfing pathogens which
Lymphocytes- pay producing antibodies
Controlling the spread of disease
A clean water supply
water can contain many different pathogens and can cause water bone diseases like Cholera
Hygienic food preparation
do not keep food at room temperature for long
wash hands before touching
keep animals away from food
Personal hygiene
Waste disposal
Sewage treatment
Remove harmful pathogens from waste before it’s released
Describe cholera
. A disease caused by a bacterium which is transmitted in contaminated water
Cholera bacterium produces a toxin that causes secretion of chloride ions into the small intestine causing osmotic movement of water into the gut, causing diarrhoea, dehydration, and loss of ions from the blood
Describe antigens and antibodies
Antibodies are proteins that bind to antigens leading to direct destruction of pathogens or marking of pathogens for destruction by phagocytosis
Specific antibodies have complimentary shapes which fit specific antigens
Each pathogen has its own antigen which have specific shapes
Antibodies, clump pathogen together and release chemicals that signal destruction of the pathogen)
Describe what happens when a pathogen enters the body and why it takes time to recover
If pathogen enters his body
Lymphocytes with antibodies that have a complimentary shape to the antigens on the pathogens will recognise the pathogen
It will quickly divide itself by mitosis
Then it will secret antibodies to destroy the pathogen
This immune response takes time as first it has to recognise the pathogen then divide which might take a day in the meantime pathogens breed making you ill
Describe memory cell
When lymphocytes makes clone not all are used to make antibodies, some remain in the blood as memory cells
Same kind of pathogen enters the body. These memory cells will already be ready and waiting for them.
Memory cells will quickly produce antibodies and destroy the pathogen before it breeds
Patient has become immune to that pathogen
Memory cells are not produced in passive immunity ~
Describe vaccination
Weekend pathogen or their antigens are inserted into the body
Antigen stimulate an immune response by lymphocytes e which produce antibodies
Memory says they’re also produced which give long-term immunity
Controlling disease by vaccination
If large enough percentage is vaccinated, it provides protection for the entire population. This is because there are very few places for the pathogen to breed.
Describe active and passive immunity
Active immunity is long-term defence from pathogens by antibody protection in the body
-Having a disease and recovering from it
-Vaccination (injected with pathogens)
Active immunity is slow acting and provides long lasting immunity
Passive immunity is a short term defence against pathogens by antibody acquired from another individual
-Breastfeeding
-Injected with antibodies
Memory cells are not made
Passive immunity as fast acting and short-term defence