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Flashcards in Chap 2 Part 1 Deck (56)
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1

Unlike epithelium, connective tissue consists mostly of what?

intercellular components and a limited number of cells

2

What are the 4 main functions of CT?

structral support, medium for exchange, defense/protection, and storage of adipose

3

What are the 4 main characteristics of CT?

derived from mesenchyme, support cells separated by matrix, support cells produce matrix, and cells adhere to matrix

4

What are the main components of the ground substance of extracellular matrix?

glycosaminoglycans, proteoglycans, adhesive glycoproteins, and other.

5

Which are larger, sulfated or non-sulfated GAGs

non-sulfated GAGs are larger molecules

6

Which type of GAGs are covalently bonded to proteins?

Sulfated GAGs

7

Which type of GAGs is important for allowing diffusion in some tissues as it holds a lot of water?

Non-sulfated GAGs

8

What are the main two positive aspects of inflammation?

increased fluidity will aid cell movement and increases numbers of defensive cells

9

What is the main negative aspect of inflammation?

excessive swelling can damage blood vessels, nerves, and cells

10

What is the term for a protein core with many sulfated GAGs attached?

proteoglycans

11

What kind of fibers are associated with CT?

reticular, elastic and collagen

12

What is the most common CT protein?

collagen

13

Wich type of collagen accounts for about 90% of the total body collagen?

Type I collagen

14

Which type of collagen is known for great tensile strength but does not stretch?

collagen I

15

T/F: As aging increases, fiber production slows and the fibers produced are stronger.

False; production slows but fibers produced are weaker (Ehlers-Danlos syndrome)

16

Which vitamin deficit is associated with weaker collagen I, bruising and bleeding gums?

Vitamin C (scurvy)

17

Which type of fiber can stretch 150% of its resting length?

elastic

18

Which type of fiber is important in blood vessels and lungs, commonly produced by fibroblasts and smooth muscle cells, and generally has fewer pathologies associated with it?

Elastic

19

As age increases, what happens to the number of elastic fibers?

decreases

20

What condition is a hereditary condition of CT, bones, muscles, ligaments and skeletal structures and is characterized by undeveloped elastic fibers?

Marfan's Syndrome

21

T/F: Marfan's Syndrome can lead to aortic aneurysm.

True

22

Which type of fiber lasts for about 3 days, is not affected by age, and is the first fiber produced during wound healing?

reticular

23

What are the 7 different cells in CT?

fibroblasts, fibrocytes, myofibroblast, adipocytes, plasma cells, macrophages, and mast cells

24

Where are fibroblasts usually derived from?

mesenchyme cells

25

When do fibroblasts primarily divide?

wound healing

26

What are the 3 main structural functions of fibroblasts?

produce/maintain matrix, produce growth factors, and scar formation

27

What are the main defensive functions of fibroblasts?

produce cytokines and enzymes and they can phagocytize when it is really needed.

28

T/F: Fibrocytes appear flatter than fibroblasts?

true

29

T/F: Fibrocytes can produce collagen I fibers and elastic fibers.

False; cannot produce either

30

T/F: Fibrocytes can produce hyloronic acid (GAGs), ground substance, and reticular fibers

True