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Flashcards in Chap 2 Part 2 Deck (33)
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1

What are the 4 events mediated by mast cells?>

asthma, anaphylaxis, immediate hypersensitivity response (simple allergy), and basic inflammatory reaction (cut in the skin)

2

What are the 5 parts of the basic inflammatory reaction?

stimulus, mast cells degranulating, histamine, then leukotrienes, and Heparin/ECF react last

3

What is the stimulus for the basic inflammatory reaction?

phagocytosis (ex. dead cells, debris, or broken fibers)

4

What are the 3 parts of the Immediate Hypersensitivity Response?

stimulus, mast cells degranulating, and localized inflammatory response

5

What is the stimulus for the immediate hypersensitivity response?

IgE and Allergins (ex. hay fever and contact dermitis)

6

What condition is described as leaky capillaries and venules below epithelium leading to urticaria (hives) and "weepy skin"

contact dermitis

7

What are the 4 parts of Anaphylaxis?

stimulus, systemic mast cell and basophil degranulation, systemic inflammatory response, and anaphylactic shock

8

What causes anaphylactic shock?

extensive internal blood loss

9

What is the stimulus for anaphylaxis?

massive IgE production

10

Which type of asthma is typically adult onset?

intrinsic asthma

11

Which type of asthma is typically childhood onset?

extrinsic asthma

12

Which type of asthma may follow a respiratory illness and the allergin is typically unknown?

intrinsic asthma

13

What stimulates asthma?

IgE allergin complex and/or secondary factors such as fatigue, emotion, temperature, food, endocrine changes

14

What is the primary problem of asthma?

release of leukotrienes leads to contraction of smooth muscles in the bronchioles leading to their closing

15

What is the secondary problem with asthma?

inflammation in the lungs

16

What are the 5 types of leukocytes discussed in class?

monocytes, neutrophils, eosinophils, basophils, and lymphocytes

17

Which type of leukocyte is attracted to sites of acute inflammation and also the most numerous of the leukocytes?

neutrophils

18

Which type of leuokcyte is attracted to sites of allergy inflammation? chronic inflammation sites?

eosinophils; lymphocytes

19

What are mesenchyme cells?

adult stem cells

20

T/F: mesenchyme cells increase with age.

False; they decrease with age

21

What are reticular cells derived from?

mesenchyme cells

22

What is the functuon of reticular cells?

to make reticular fibers when needed on a permanent basis

23

What are the 2 classifications of CT?

CT proper and specialized CT

24

What are the 4 types of CT proper?

loose CT, dense CT, reticular CT and adipose

25

Which type of CT proper has a larger number of cells/cell types, fewer fibers, increased GAGs, and is quite vascular?

Loose CT

26

What are the 2 types of Loose CT?

loose areolar and loose irregular

27

Which type of CT proper has fewer cells/cell types, many fibers, decreased amounts of ground substance and are less vascular?

Dense CT

28

What are the 2 types of Dense CT?

dense irregular and dense regular

29

Which type of CT proper can be found in lymphatic and endocrine organs?

Reticular CT

30

Which highly vascular type of CT proper functions as an energy source, cushion organ, and a thermoregulator?

adipose